نتایج جستجو برای: 6-Azauracil
تعداد نتایج: 956322 فیلتر نتایج به سال:
We report the photoelectron spectrum of the 6-azauracil anion. The spectrum is dominated by a broad band exhibiting a maximum at an electron binding energy (EBE) of 1.2 eV. This spectral pattern is indicative of a valence anion. Our calculations were carried out using ab initio electron propagator and other many-body methods. Comparison of the anion and corresponding neutral of 6-azauracil with...
The antibacterial activity of 2-thiouracil, 2-methylthiouracil, 2-hydrazinouracil, 2,4-dithiouracil, 2-thio-4-hydrazinouracil, 2-thio-6-azathymine, 2-hydrazino-6-azathymine, 2,4-dithio-6-azathymine, 2-thio-4-hydrazino-6-azathymine, 2,4-dimethylthio-6-azathymine, 2-methylthio-4-hydrazino-6-azathymine, 4-thio-6-azauracil and 4-hydrazino-6-azauracil has been studied on the growth o f : Staphylococ...
http://www.revistadechimie.ro 964 It is established that analogues of natural nucleobases and nucleosides, containing nitrogen atoms have good antimetabolite [1, 2], antiviral, antibacterial [3, 4] antitumor and antimetastatic properties [5]. One of the first compounds obtained, exhibiting good antitumor and antimetabolite activity is 6-azauridine, an analogue of 6azauracil [2]. In recent years...
3-Arylhydrazono-2,4-dioxo-4-phenylbutanoateshave been prepared by the coupling of benzoylpyruvate with aryldiazonium chlorides.Reactions ofthe 3-arylhydrazono-2,4-dioxo-4-phenylbutanoateswith 1-aminoguanidine, semicarbazide, and thiosemicarbazidegave5-substituted 2-imino-6-azauracil (3a),6-azauracil (3b), and 2-thio-6-azauracil (3c), respectively. The analytical data of these compounds - IR, 1H...
Azauracil was found to be the only one of several analogs of nucleic acid precursors tested in these studies which is capable of inducing tumors at a very early stage during seedling development in the genetically tumor-conditioned hybrid Nicotiana glauca • N. Iangsdorffii. Tumor induction by 6-azauracil was shown to be reversed by simultaneous treatments with uracil and actinomycin D as well a...
3-Arylhydrazono-2,4-dioxo-4-phenylbutanoates have been prepared by the coupling of benzoylpyruvate with aryldiazonium chlorides. Reactions of the 3-arylhydrazono-2,4- dioxo-4-phenylbutanoates with 1-aminoguanidine, semicarbazide, and thiosemicarbazide gave 5-substituted 2-imino-6-azauracil (3a), 6-azauracil (3b), and 2-thio-6-azauracil (3c), respectively. The analytical data of these compounds ...
Azauracil was found to be the only one of several analogs of nucleic acid precursors tested in these studies which is capable of inducing tumors at a very early stage during seedling development in the genetically tumor-conditioned hybrid Nicotiana glauca • N. Iangsdorffii. Tumor induction by 6-azauracil was shown to be reversed by simultaneous treatments with uracil and actinomycin D as well a...
Cotton (Gossypium hirsutum L.) ovules grown in a defined nutrient medium undergo normal morphogenesis, including fiber production. In identical medium lacking boron, ovules callus and accumulate brown substances. Boron deficiency-like symptoms were induced by 6-azauracil and 6-azauridine in ovules growing in boron-sufficient media. Other nucleoside base analogs either reduced or had no effect o...
Previous work has shown that the asymmetric triazine analogue of uridine, 6-azauracil riboside (azauridine), is a much more potent inhibitor of the growth of transplantable mouse tumors than is 6-azauracil (1,2). Presumably this difference in activity reflects the limited extent of the conversion of azauracil to azauridine in mammalian systems (3). On the other hand, formation of the 5’-phospha...
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