The in vitro activities of Y-688, a new 7-substituted fluoroquinolone derivative, against 317 nonduplicate anaerobic isolates were determined. Eighty-five percent of the Bacteroides fragilis group (n = 89) were inhibited by < or = 2 mg of Y-688 per liter, while 78, 100, 89, and 98% of gram-negative bacilli (n = 135), gram-positive cocci (n = 59), and non-spore-forming (n = 58) and spore-forming...

A phytochemical investigation of the acetone extract from the immature fruits of Garcinia cowa led to the isolation of two novel tetraoxygenated xanthones, garcicowanones A (1) and B (2), together with eight known tetraoxygeanted xanthones. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their antibacterial activity against Bacillus cereus T...

INTRODUCTION........................................... 60 ADENYLATE CYCLASE FROM B. PERTUSSIS ........................................... 60 CALMODULIN REGULATION ........................................... 61 PATHOGENICITY AND CELL INVASION ........................................... 61 PURIFICATION AND CHARACTERIZATION ........................................... 62 ADENYLATE CYCLASE FROM BAC...

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,144 5.7 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,037 5.2 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1,251 6.3 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2,143 10.7 20 to 24 years . . . . . . . . . . . . . . . . ...

As a pollen feeder, Propylea japonica would be directly exposed to Cry proteins in Bacillus thuringiensis (Bt)-transgenic rice fields. The effect of Cry1C- or Cry2A-containing transgenic rice pollen on the fitness of P. japonica was assessed using two dietary-exposure experiments in the laboratory. In the first experiment, larval developmental time of P. japonica was significantly longer when f...

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 688 8.7 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 700 8.9 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 740 9.4 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 714 9.0 20 to 24 years . . . . . . . . . . . . . . . . . . . . ....

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2,405 6.5 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2,278 6.1 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2,169 5.8 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2,971 8.0 20 to 24 years . . . . . . . . . . . . . . . . ....

Joint Center for Articial Photosynthes Pasadena, California 91125, USA. E-mail: g Joint Center for Articial Photosynthesis, Berkeley, California 94720, USA Engineering Division, Lawrence Berkeley N 94720, USA Department of Chemical and Biomolecular Berkeley, Berkeley, California 94720, USA † Electronic supplementary information additional electrochemical data, SEM electrolyzer data, compariso...

To date, the in vitro–in vivo correlation (IVIVC) of P-glycoprotein (P-gp)–mediated drug-drug interaction (DDI) at the blood-brain barrier (BBB) in rats indicated that the cutoff value to significantly affect the brain penetration of digoxin was [I,unbound/Ki] of 1, where I,unbound is the unbound plasma concentration of P-gp inhibitors. On the basis of the IVIVC in rats, we speculated that clin...

Background: Obesity is the most important risk factor for obstructive sleep apnea (OSA). Weight-reduction programs have been observed to represent effective treatment of overweight patients with OSA. However, it is not known whether beneficial changes remain after the end of the intervention. Objective: The aim of the study was to assess the long-term efficacy of a lifestyle intervention based ...