Background Several treatment options have been described for chronic rhinosinusitis (CRS), yet many patients remain poorly responsive to medical and surgical therapy. Recently, antiIgE monoclonal antibody has emerged as a potential therapy for CRS. However, to date evidence for its efficacy in this patient population is sparse. The purpose of this study is to evaluate the clinical effect of ant...

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cept can serve as a basis for identifying subgroups that are in need of programmatic action. Unmet need rises as more women would like to control their fertility but for various reasons are unable to do so, and it falls as more start practicing contraception. However, high levels of unmet need in a country do not necessarily reflect program failure, nor do low levels always indicate program suc...