Palladium-catalyzed ring-opening reactions of cyclopropanated 7-oxabenzonorbornadiene derivatives using alcohol nucleophiles were investigated. The optimal conditions were found to be 10 mol % PdCl2(CH3CN)2 in methanol, offering yields up to 92%. The reaction was successful using primary, secondary and tertiary alcohol nucleophiles and was compatible with a variety of substituents on cyclopropa...

This paper presents a new three-dimensional shape descriptor: 3D angular radial transform. It is an extension of the 2D region based shape descriptor proposed by MPEG7, the Angular Radial Transform (ART). We propose to generalize the ART to index 3D models.

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Variable sensitivity to T-cell-receptor (TCR)- and IL-7-receptor (IL-7R)-mediated homeostatic signals among naïve T cells has thus far been largely attributed to differences in TCR specificity. We show here that even when withdrawn from self-peptide-induced TCR stimulation, CD8(+) T cells exhibit heterogeneous responses to interleukin-7 (IL-7) that are mechanistically associated with IL-7R expr...

Reading a book is also kind of better solution when you have no enough money or time to get your own adventure. This is one of the reasons we show the developments in telecommunications with a focus on ss7 network reliability as your friend in spending the time. For more representative collections, this book not only offers it's strategically book resource. It can be a good friend, really good ...

For high-accuracy template-based-modeling of CASP7 targets, we have applied a procedure based on the rigorous optimization of score functions at three stages: multiple alignment, chain building, and side-chain modeling. We applied the conformational space annealing method to a newly developed consistency based score function for multiple alignment. For chain building, we optimized the MODELLER ...

In this paper we give an overview of challenges and chances of the integration of methylation data into Electronic Health Records. Perspectives of methylation data in terms of clinical relevance and characteristics of these data are shown. Among several standards OpenEHR, HL7 CG and LOINC are identified as starting point for the representation and communication of methylation data within the cl...