The cortical processing of umami shows what makes it pleasant and appetitive. The pleasantness of umami reflects and is correlated with processing in the secondary taste cortex in the orbitofrontal cortex and tertiary taste cortex in the anterior cingulate cortex, whereas processing in the primary (insular) taste cortex reflects physical properties such as intensity. However, glutamate presente...

Disturbances of neuronal excitability changes during the ovarian cycle may elevate seizure frequency in women with catamenial epilepsy and enhance anxiety in premenstrual dysphoric disorder (PMDD). The mechanisms underlying these changes are unknown, but they could result from the effects of fluctuations in progesterone-derived neurosteroids on the brain. Neurosteroids and some anxiolytics shar...

Background: Epidemiologic studies show an inverse or U-shaped relation between sleep duration and BMI. Decreases in total energy expenditure (TEE) and physical activity have been suggested to be contributing factors. Objective: The objective was to assess the effect of sleep fragmentation on energy metabolism and energy balance in healthy men. Design: Fifteen healthy male subjects [mean6 SD BMI...

Sustainable Business: Opportunity and Value Creation Andrea L. Larson Assistant Professor of Business Administration Darden Graduate School of Business Administration University of Virginia P.O. Box 6550 Charlottesville, Virginia 22906-6550 (804) 924-3221 (804) 243-7677 fax [email protected] Elizabeth Olmsted Teisberg Associate Professor of Business Administration Darden Graduate...

OBJECTIVE To evaluate long-term outcomes of adjunctive therapy with SPN-804 (Oxtellar XR® , Supernus Pharmaceuticals), an extended-release tablet formulation of oxcarbazepine (OXC), in adults with refractory partial-onset seizures. METHODS After completing a 16-week double-blind, placebo-controlled trial of SPN-804 at fixed dosages (1200 or 2400 mg QD), patients entering this open-label exten...

Correspondence: Dr. Steven Grant, Division of Hematology/Oncology, MCV Station Box 230, Virginia Commonwealth University, Richmond, VA 23298, Phone: 804-828-5211, Fax: 804828-8079, Email: [email protected], or Dr. Mohamed Rahmani, Virginia Commonwealth University, Massey Cancer Center, 401 college street, P.O. Box 980035, Richmond VA 23298. Phone: 804-628-1976, Fax: 804-225-3788, E-mail: mrah...

Dr. Etti G. Baranoff, FLMI Associate Professor of Insurance and Finance Department of Finance, Insurance and Real Estate School of Business Virginia Commonwealth University Snead Hall, 301 West Main Str., Suite B4167 Richmond VA 23284-4000 Tel: 804-828-3187, Fax: 804-828-3972 Cell: 512-750-6782 www.professorofinsurance.com [email protected] or [email protected] & Research Director, Insurance a...

1. Abstract 2. Introduction 2.1. History and successes of cancer immunotherapy 2.2. Viruses and cancer therapy 3. Identification of tumor associated antigens 4. Ideal properties of an antigen delivery system 4.1. Why are viral vectors suitable for delivering TAAs? 5. Poxvirus vectors 5.1. Vaccinia virus 5.1.1. Use of vaccinia viral vectors to deliver tumor antigens 5.1.1.1. Carcinoembryonic ant...

Richard P. Wenzel, M.D., M.Sc. Department of Internal Medicine Virginia Commonwealth University One Capital Square, 2 nd floor 830 East Main Street Phone: (804) 828-5388 Fax: (804) 628-2769 Email: [email protected] Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Antimicrob. Agents Chemother. doi:10.1128/AAC.00438-10 AAC Accepts...

While antenatal corticosteroids (ACS) administered in the late preterm period have been shown to reduce neonatal respiratory morbidity, this finding was demonstrated a well-designed randomized controlled trial (ALPS) with strict inclusion/exclusion criteria that may not be adhered typical practice. The aim of study investigate whether there has treatment creep since use ACS became standard care...