The binding dynamics of the 2-aminoanthracenium cation (AH(+)) and 2-aminoanthracene (A) with cucurbit[7]uril (CB[7]) was studied using stopped-flow experiments. The kinetics was followed by measuring the fluorescence changes over time for AH(+) and A, which emit at different wavelengths. The studies at various pH values showed different mechanisms for the formation of the AH(+)@CB[7] complex, ...

We investigated the effects of prostaglandin E2 (PGE2) on amyloid precursor protein (APP) expression in cultured rat microglia. PGE2 treatment significantly increased the expression of APP holoprotein and was associated with an elevation in cyclic AMP (cAMP). Direct activation of adenylate cyclase with forskolin also increased APP expression. Co-treatment of microglia with PGE2 and the PKA inhi...

Abu Hamamid (AH) Neoproterozoic (Sm/Nd model age of 770 ± 20 Ma) mafic–ultramafic intrusion lies along a NE–SW fracture zone in the Shadli Metavolcanic Belt, south Eastern Desert, Egypt. AH intrusion is concentrically zoned with cumulate clinopyroxenebearing dunite core mantled by olivine clinopyroxenite, hornblende clinopyroxenite and hornblende gabbroic rim. The observed crystallization seque...

Cyooxygenase-2 (COX-2)-derived PGE2 is critical for the integrity and function of renal medullary cells during antidiuresis. The present study extended our previous finding that tonicity-induced COX-2 expression is further stimulated by the major COX-2 product PGE2 and investigated the underlying signaling pathways and the functional relevance of this phenomenon. Hyperosmolality stimulated COX-...

Replicated cow herds of 15 Angus x Hereford (AH) and 15 Brahman x Hereford (BH) F1 cows each were placed on native rangeland (NR) or native rangeland-complementary forage (NRCF) systems. The NR was 8.1 ha of sagebrush-mixed prairie per cow-calf unit and the NRCF used the same mixed prairie complemented by .4 ha of double-cropped winter wheat and summer annual forage replacing about 30% of the m...

A constant intravenous infusion of phenylephrine (0.74 +/- 0.41 micrograms/kg/min) was given to 10 patients to cause a continuous augmentation in reflex vagal tone. After the infusion, the diastolic blood pressure increased from 76 +/- 7 to 89 +/- 11 mm Hg (p less than 0.01). The sinus cycle length and atrial-His (AH) interval were measured, and incremental atrial pacing was performed before an...

In this study, 19 experiments were conducted with 25 pouch cells of NMC cathode to investigate thermal runaway and the release gases from lithium-ion batteries (LIBs). Single cells, double a four-cell battery stack forced undergo inside an air-tight reactor vessel volume 100 dm3. The study involved two series tests types ignition sources. Series 1 tests, heating plug was used initiate in LIBs r...

the second half of the third hijri century, coinciding with the reign of three caliphs, al-mu’tamid (256-79 ah), al-mu’tadhid (279-89 ah), and al-muktafi (289-95 ah), abbasids restored their authority and renewed their organization. this reform process which was began by abu ahmad al-muwaffaq (d. 278 ah) and reached its climax at the time of abu al-abbas al-mu’tadhid stood between two decline p...

The mortality rate of alveolar hemorrhage (AH) after allogeneic hematopoietic stem cell transplantation is greater than 60% with supportive care and high-dose steroid therapy. We performed a retrospective cohort analysis to assess the benefits and risks of recombinant human factor VIIa (rFVIIa) as a therapeutic adjunct for AH. Between 2005 and 2012, 57 episodes of AH occurred in 37 patients. Fo...