نتایج جستجو برای: A (Diphenylpropane)

تعداد نتایج: 13431818  

Journal: :Organic letters 2018
David G Twigg Leonardo Baldassarre Elizabeth C Frye Warren R J D Galloway David R Spring

The first total synthesis of bussealin E, a natural product with a unique cycloheptadibenzofuran scaffold, is reported. A strategy inspired by a proposed biosynthesis was employed whereby a diphenylpropane derivative underwent an oxidative phenolic coupling to forge the tetracyclic ring system. The synthesis of the diphenylpropane featured a key sp2-sp3 Hiyama coupling between a vinyldisiloxane...

2004
Dietmar Kuck

The mechanism of the formation of [C,Hs]' ions by hydrogen rearrangement in the molecular ions of 1-phenylpropane and 1,3-diphenylpropane has been investigated by looking at the effects of CH,O and CF, substituents in the meta and para positions on the relative abundances of the corresponding ions and on the appearance energies. The formation of [C,H,]' ions from 1,3-diphenylpropane is much enh...

2004
Dietmar Kuck

Hydrogen migrations in the molecular ions of 1,3-diphenylpropane, preceding the fragmentations to [C7H,]' and [C,H& ions, have been investigated by use of deuterated derivatives. By comparing the distribution of deuterium labels in the [C,(H, D)Jt products from metastable molecular ions with the distribution patterns calculated for various exchange models, it is shown that the H migrations occu...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2005
Shigeyuki Kitamura Tomoharu Suzuki Seigo Sanoh Ryuki Kohta Norimasa Jinno Kazumi Sugihara Shin'ichi Yoshihara Nariaki Fujimoto Hiromitsu Watanabe Shigeru Ohta

The endocrine-disrupting activities of bisphenol A (BPA) and 19 related compounds were comparatively examined by means of different in vitro and in vivo reporter assays. BPA and some related compounds exhibited estrogenic activity in human breast cancer cell line MCF-7, but there were remarkable differences in activity. Tetrachlorobisphenol A (TCBPA) showed the highest activity, followed by bis...

2014
Oleg N. Starovoytov Yalin Liu Liuxi Tan Shizhong Yang

Bisphenol-A (4,4'-dihydroxy-2,2-diphenylpropane, BPA, or BPA-A) and its derivatives, when exposed to humans, may affect functions of multiple organs by specific binding to the human estrogen-related receptor γ (ERRγ). We carried out atomistic molecular dynamics (MD) simulations of three ligand compounds including BPA-A, 4-α-cumylphenol (BPA-C), and 2,2-diphenylpropane (BPA-D) binding to the lig...

Journal: :Acta Crystallographica Section E Structure Reports Online 2010

Journal: :Mycopathologia 1997
F Pinot E D Caldas C Schmidt D G Gilchrist A D Jones C K Winter B D Hammock

Using trans-diphenylpropane oxide (tDPPO) as a substrate, we measured epoxide hydrolase (EH) activity in subcellular fractions of Alternaria alternata f. sp. lycopersici (Aal), a fungus that produces host-specific toxins. The activity was mainly (> 99.5%) located in the soluble fraction (100,000 x g supernatant) with the optimum pH at 7.4. An increase of toxin production between days 3 and 9 fo...

Journal: :Environmental Health Perspectives 2003
Shigeyuki Kitamura Motoko Ohmegi Seigo Sanoh Kazumi Sugihara Shin'ichi Yoshihara Nariaki Fujimoto Shigeru Ohta

In this study we examined estrogenic activity of styrene oligomers after metabolic activation by rat liver microsomes. Trans-1,2-diphenylcyclobutane (TCB), cis-1,2-diphenylcyclobutane (CCB), 1,3-diphenylpropane, 2,4-diphenyl-1-butene, 2,4,6-triphenyl-1-hexene, and 1-alpha-phenyl-4ss-(1 -phenylethyl)tetralin were negative in the yeast estrogen screening assay and estrogen reporter assay using es...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید