OBJECTIVE Oocyte maturation process characterizes polycystic ovary syndrome (PCOS). The mechanisms of this abnormality leading to chronic anovulation are under investigation. Advanced glycosylated end products (AGEs), a marker of oxidative stress linked with oocyte maturation are localized in granulosa cells and are increased in sera, in women with PCOS. The aim of this study was to investigate...

The classical Ka?anov scheme for the solution of nonlinear variational problems can be interpreted as a fixed point iteration method that updates given approximation by solving linear problem in each step. Based on this observation, we introduce modified Ka ? anov , which allows (adaptive) damping, and, thereby, to derive new convergence analysis under more general assumptions and wider range a...

OBJECTIVE Patients with polycystic ovary syndrome (PCOS) diagnosed with the 1990 criteria (i.e. presence of oligo- and/or anovulation (ANOV) and hyperandrogenemia and/or hyperandrogenism (HA) with or without polycystic ovaries (PCO)) appear to have a more adverse metabolic profile than patients diagnosed with the additional criteria introduced in 2003 (i.e. presence of HA and PCO without ANOV a...

The objective of the study was the comparison of anti-Müllerian hormone (AMH) levels among obese or overweight and normal-weight women with the four different polycystic ovary syndrome (PCOS) phenotypes and healthy control subjects. AMH levels were evaluated in four age- and body mass index (BMI)-matched groups of 25 normal-weight and 25 obese or overweight women each, belonging to the four mai...

BACKGROUND No data regarding metformin effects on follicular fluid anti-Müllerian hormone (AMH) levels were to date available in literature. The aim of the present study was to evaluate in patients with polycystic ovary syndrome (PCOS) whether metformin administration affects serum and follicular AMH levels, and whether this is related to ovarian response to the treatment. METHODS Twenty youn...

Cohort Profile: The European Longitudinal Study of Pregnancy and Childhood (ELSPAC) in the Czech Republic Pavel Piler, V ıt Kandrnal, Lubom ır Kukla, Lenka Andr yskov a, Jan Svancara, Ji r ı Jarkovsk y, Ladislav Du sek, Hynek Pikhart, Martin Bob ak and Jana Kl anov a* Research Centre for Toxic Compounds in the Environment (RECETOX), Institute of Biostatistics and Analyses, Masaryk University, B...

OBJECTIVE The aim of this study was to determine the cardiometabolic risk factors in different polycystic ovary syndrome (PCOS) phenotypes. SUBJECTS AND METHODS This cross-sectional study was performed between 2010 and 2011. Eighty-nine patients with PCOS and 25 age- and weight-matched healthy controls were included in the study. Patients were grouped using the Rotterdam 2003 criteria as: gro...

Retronasal (retro) and/or oral-cavity-only (OeD) smelling of vapor-phase agonists for the trigeminal chemoreceptive ion channel TRPM8 was studied. In a retro and OeD identification experiment. 1 of 6 previously practiced identifications (ID) was selected on a computer display under forced-choice conditions. Analyses of variance (ANOV A) found differences across odorants and retro and OeD. and f...

Confidence intervals have a long history and have become an indispensable tool in statistical applications. The computation of confidence intervals for a mean based on normal (large sample) theory is straightforward and readily available in the SAS system through such procedures as PROC ANOV A and PROC GLM. For the case of small samples and non-normal distributions, however, normal theory based...