Selective acylation of alcohol has enjoyed great attraction of chemists due to its significance in synthetic organic chemistry especially in protecting group chemistry as reflected by the number of methods that have been developed to effect this transformation. To meet the challenging task of chemoselective transformation of aliphatic alcohols in the presence of phenolic alcohol mainly acidic c...

Benzene, halobenzenes and some deactivated arenes readily reacted in anhydrous NaIO4/AcOH/Ac2O/concd. H2SO4 mixtures to afford, after quenching with excess aqueous Na2SO3 solution (a reducing agent), purified iodinated products in 27-88% yields. This novel method of aromatic iodination is simple, fairly effective and environmentally safe.

This paper reports a one-pot synthesis of the title bromides from both activated and deactivated iodoarenes which are first oxidized with anhydrous NaBO3·H2O/Ac2O/conc.H2SO4 liquid mixtures, then coupled in situ with benzene and activated arenes and, finally, precipitated out with a KBr solution; this method is easy, cheap, safe and fairly effective.

Benzene, halobenzenes, and a number of more or less deactivated arenes,including nitrobenzene, readily reacted in anhydrous HIO3/AcOH/Ac2O/conc. H2SO4 mixtures to probably give ArIO2 intermediates or other hypervalent species (not isolated). The final reaction mixtures were poured into excess aq. Na2SO3 solution (a reductant) to give the purified iodinated products in 39-83% yields.

An easy and safe, though only moderately effective method is presented for preparing (diacetoxyiodo)arenes, ArI(OAc)2, from iodoarenes, ArI, using the commercially available and easily handled urea-hydrogen peroxide adduct (UHP) as the oxidant. The reactions take place in anhydrous AcOH/Ac2O/AcONa (a catalyst)mixtures, at 40 oC for 3.5 h to afford the purified ArI(OAc)2 in 37-78% yields. The fu...

Postglycosylation acetylation of sialic acid imparts unique roles to sialoglycoconjugates in mammalian immune response making structural and functional understanding of these analogues important. Five partially O-acetylated Neu5Ac analogues have been synthesized. Reaction of per-O-silylated Neu5Ac ester with AcOH and Ac2O in pyridine promotes regioselective silyl ether/acetate exchange in the f...

give faint yellow crystals, m.p. 235°. It was soluble in NaHCO3 solution and gave brown coloration with FeCl3. Anal. Found: C, 66.76, 66.37; H, 5.44, 5.37. Acetylation of (I)-A mixture of 10g. of (I), 100cc. of Ac2O and 20 drops of conc. H2SO4 was warmed on a water bath for 3hr. and after cooling, the mixture was poured into ice water. Brown precipitates that separated out were treated with MeO...

The aim in this study was first to explain, detail the conversion of diacetates over time into chlorinated monoacetates following ether cleavage with AcCl norcantharimide derivatives help NMR technique and second, verify theoretically computationally. Ether reactions N-methyl, N-benzyl, N-acetoxyethyl-substituted were performed Ac2O or presence H2SO4, mechanisms these elucidated detail. Accordi...