نتایج جستجو برای: Agr protein

تعداد نتایج: 1235864  

2014
Xiao-Jing Du Ling-Long Tang Yan-Ping Mao Ying Sun Mu-Sheng Zeng Tie-Bang Kang Wei-Hua Jia Ai-Hua Lin Jun Ma

BACKGROUND Low serum albumin is predictive of poor survival in nasopharyngeal carcinoma (NPC). We evaluated the ability of the pretreatment albumin/globulin ratio (AGR) to predict long-term mortality in patients with NPC. METHODS This retrospective study examined an unselected cohort of 694 patients with NPC who had documented pretreatment total serum protein and serum albumin levels (ALB). A...

Journal: :Infection and immunity 1997
A L Cheung K Eberhardt J H Heinrichs

The synthesis of protein A in Staphylococcus aureus is regulated by global regulatory loci such as sar and agr. Phenotypic data indicate that both sar and agr suppress protein A synthesis; like agr, sar also regulates protein A production at the transcriptional level. To determine the genetic requirement of sar in protein A suppression, we transformed shuttle plasmids containing various sar fra...

Journal: :The Journal of biological chemistry 1999
Y Chien A C Manna S J Projan A L Cheung

The expression of many virulence determinants in Staphylococcus aureus including alpha-hemolysin-, protein A-, and fibronectin-binding proteins is controlled by global regulatory loci such as sar and agr. In addition to controlling target gene expression via agr (e.g. alpha-hemolysin), the sar locus can also regulate target gene transcription via agr-independent mechanisms. In particular, we ha...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ارومیه - دانشکده دامپزشکی 1391

استافیلوکوکوس اورئوس می تواند در مخاط بینی دام های مختلف کلونیزه شود. تنظیم کننده ژنی فرعی (agr) یک مجموعه از ژن های موثر در شناخت حد نصاب(quorum sensing) می باشد که جایگزینی و حدت را در استافیلوکوکوس اورئوس کنترل می کند. در مطالعه حاضر، گروه های agr 26 جدایه استافیلوکوکوس اورئوس بدست آمده از بینی گاو (چهار جدایه)، گوسفند (11 جدایه) و بز (11 جدایه) با استفاده از روش مولتیپلکس pcr از نظر تیپ agr...

2017
Xiaobo He Shengjie Guo Dong Chen Guangwei Yang Xin Chen Yijun Zhang Qiuming He Zike Qin Zhuowei Liu Yunfei Xue Meng Zhang Ruiwu Liu Fangjian Zhou Hui Han Kai Yao

Background: Malnutrition and systemic inflammatory response are frequently associated with prognosis in patients with several types of cancer, including renal cell carcinoma (RCC). The study is aimed to investigate the ability of preoperative serum albumin to globulin ratio (AGR) to predict the long-term mortality of RCC patients. Methods: The study is a retrospective study of an unselected coh...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2014
Ayse Ocak Duran Mevlude Inanc Halit Karaca Imran Dogan Veli Berk Oktay Bozkurt Ersin Ozaslan Mahmut Ucar Celalettin Eroglu Metin Ozkan

BACKGROUND Prior studies showed a relationship between serum albumin and the albumin to globulin ratio with different types of cancer. We aimed to evaluate the predictive value of the albumin-globulin ratio (AGR) for survival of patients with lung adenocarcinoma. MATERIALS AND METHODS This retrospective study included 240 lung adenocarcinoma patients. Biochemical parameters before chemotherap...

2017
Jianjun Liu Shangxiang Chen Qirong Geng Xuechao Liu Pengfei Kong Youqing Zhan Dazhi Xu

BACKGROUND Several studies have highlighted the prognostic value of the albumin-globulin ratio (AGR) in various kinds of cancers. Our study was designed to assess whether AGR is associated with the prognosis of gastric cancer patients. PATIENTS AND METHODS A total of 507 gastric cancer patients between 2005 and 2012 were included. The AGR was defined as the ratio of serum albumin to nonalbumi...

ژورنال: Medical Laboratory Journal 2016
Moradi , Abdolvahab, Ghaemi , Ezzat Allah , Koohsari , Hadi , Mozaffari , Nour Amir ,

Abstract       Background and Objective: Agr is the most important regulatory system for the expression of Staphylococcus aureus virulence factors in different conditions. Agr acts as a quorum sensing system in this bacterium which is activated by increased cell concentration during the transition from logarithmic growth phase to stationary phase. Its role is to up...

Journal: :Infection and immunity 2007
Yasuhiko Matsumoto Chikara Kaito Daisuke Morishita Kenji Kurokawa Kazuhisa Sekimizu

We previously reported that the cvfB gene (SA1223) of Staphylococcus aureus is responsible for the virulence of this pathogenic bacterium. We show here that the cvfB gene regulates exoprotein gene expression. In a cvfB gene deletion mutant, hemolysin, DNase, and protease production were decreased, whereas protein A expression was increased. The amount of RNAIII, the transcript from the P3 promo...

2015
Bo Zhang Wei Yu Li-Qun Zhou Zhi-Song He Cheng Shen Qun He Jun Li Li-Bo Liu Cong Wang Xiao-Yu Chen Yu Fan Shuai Hu Lei Zhang Wen-Ke Han Jie Jin Xin Gao

BACKGROUND Preoperative albumin-globulin ratio (AGR) reflects both malnutrition and systemic inflammation in cancer patients. In particular, systemic inflammation has been reported to contribute to tumor progression and poor oncological outcome in various malignancies. However, the prognostic value of preoperative AGR in upper tract urothelial carcinoma (UTUC) has not been examined. METHODS W...

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