the purpose of this study was to evaluate the changes in the serum concentrations of haptoglobin (hp), serum amyloid a (saa) and igg, iga in calves with diarrhea caused by rotavirus, coronavirus, escherichia coli f5 and eimeria species. the experiment was carried out on 40 diarrhoeic and 10 non-diarrhoeic calves (group c). a total of 13 calves were infected with rotavirus or coronavirus (group ...

to evaluate the serum concentrations of haptoglobin (hp) and serum amyloid a (saa) in water buffaloes with abomasal ulcers, the abomasums of 100 randomly selected water buffaloes were examined after slaughter. type i abomasal ulcers were found in 56 out of 100 buffaloes. serum concentrations of hp and saa were measured. there was no significant difference between affected and non-affected buffa...

this study was designed to evaluate serum and milk amyloid a (saa) as an inflammatory indicator in inflammatory diseases. twenty clinically healthy cows and 100 cows with various inflammatory diseases were selected for this study. blood samples were collected from the coccygeal vein of both healthy and diseased groups. milk samples were taken from four quarters of both groups. milk samples of f...

amyloidoma or amyloid tumor is a tumor-like localized deposit of amyloid encountered occasionally in association with multiple myeloma, various chronic inflammatory diseases and primary amyloidosis. amyloid tumors unassociated with plasmacytoma or other disease are extremely rare in soft tissues and few cases in various situations have been reported. histologic examination discloses amorphous e...

introduction: diagnosing and treating diseases associated with amyloid fibers remain a great challenge despite of intensive research carried out. one important approach in the development of therapeutics is the use of herbal extracts which are rich in aromatic small molecules. cinnamomum verum extract (ce) contains proanthocyanidin and cinnamaldehyde, which have been suggested to be capable of ...

the objective of this study was to evaluate the concentration of these acute phase proteins(serum amyloid a, milk amyloid a and serum haptoglobin) and alteration in hematological values in some inflammatory diseases in dairy cattle. fifty-six holstein dairy cows with some inflammatory diseases were used in this study including: subclinical mastitis, hematological infections (theileriosis and an...

Background & Aims: Alzheimer's disease is a neurodegenerative disorder characterized by the abnormal aggregation of amyloid-β plaques in the brain. Although several studies have been done for finding effective medicines in the treatment of this disease, a drug that inhibits amyloid β aggregation and ameliorates the disorder has not been approved so far. One important therapeutic approach is use...

Familial amyloid polyneuropathy (FAP) type IV (FINNISH) is a rare clinical entity with challenging neuropathy and cosmetic deficits. Amyloidosis can affect peripheral sensory, motor, or autonomic nerves. Nerve lesions are induced by deposits of amyloid fibrils and treatment approaches for neuropathy are challenging. Involvement of cranial nerves and atrophy in facial muscles is a real concern i...

Alzheimer’s disease (AD) is a neuroinflammatory based pathologic state in which β-amyloid aggregates are a major devastating agents. In this study, a series of 2-hydroxyiminoethanones were synthesized and evaluated as anti-inflammatory in carrageenan and formalin tests and inhibitors of β-amyloid aggregation. Compounds 1-10b were synthesized through a two-step reaction. Results: Compounds 1-5b ...

objective: to study the mechanisms involved in amyloid formation processes, we made a mammalian cell culture model of amylin aggregation and characterized its properties. materials and methods: amyloid fibrils were extracted from cho cells and binding affinity to thioflavin t and congo red was investigated. then the apple-green birefringence of extracted fibrils was detected under polarized li...