anti-androgens are an assorted group of drugs and compounds that reduce the levels or activity of androgen hormones within the human body. disease states in which this is relevant include polycystic ovarian syndrome, hirsutism, acne, benign prostatic hyperplasia, and endocrine related cancers such as carcinoma of the prostate. we provide an overview and discussion of the use of anti-androgen me...

introduction: nymphea lotus linn (n. lotus) flowers are used empirically for the treatment of male sexual disorders in cameroon west region. this study was aimed to evaluate the effects of the n. lotus on some parameters of male fertility in adult albino male rats. methods: twenty four male rats were divided in 4 groups (n=6 each) and subjected to the following treatment: distilled water as veh...

to assess the relative contribution of genetic and environmental factors (particularly androgens) on circulating levels of lipid fractions, serum androgen and lipid fractions were measured in 34 pairs of female-female twins aged from 15- 45 years, some of whom were discordant for polycystic ovary syndrome (pcos) diagnosed by ultrasound. nineteen pairs were monozygotic twins (mz) and 15 pairs we...

Aim: Androgens are hormones that essential for the differentiation and development of male genital organs, preserving their structural features maintaining functions. These exert effects on target tissues mainly through androgen receptors (AR). The aim this study was to determine AR immunoexpression pattern in mice. Materials Methods: A total 6 BALB/c mice were anesthetized with ether, tissues,...

Aging, as a major risk factor of memory deficiency, affects neural signaling pathways in hippocampus. In particular, age-dependent androgens deficiency causes cognitive impairments. Several enzymes like protein kinase C (PKC) are involved in memory deficiency. Indeed, PKC regulatory process mediates α-secretase activation to cleave APP in β-amyloid cascade and tau proteins phosphorylation mecha...

background : androgens have been shown to have diverse effects on the cardiovascular system. the aim of this study was to compare androgenic hormone levels in patients with different left ventricular ejection fractions (ef). methods : the study population consisted of 515 consecutive men who were referred for angiographic studies and whose results of echocardiography and coronary angiography we...