introduction: acute idiopathic thrombocytopenic purpura (itp) is an autoimmune bleeding disorder of childhood caused by production of auto antibodies against platelets. the aim of the present study was to compare the efficacy of intravenous immunoglobulin (ivig) and intravenous anti-d(iv anti-d) in itp treatment. methods and materials: in a clinical trial, 43 children with acute itp referred to...

rhd antigen is the most immunogenic and clinically significant antigen of red blood cells after abo system. it has historically been associated with hemolytic disease of the newborn (hdn) which is now routinely prevented by the administration of polyclonal anti-d immunoglobulin. this management of hdn has proven to be one of the most successful cases of prophylactic treatment based on antibody ...

RhD antigen is the most immunogenic and clinically significant antigen of red blood cells after ABO system. It has historically been associated with hemolytic disease of the newborn (HDN) which is now routinely prevented by the administration of polyclonal anti-D immunoglobulin. This management of HDN has proven to be one of the most successful cases of prophylactic treatment based on antibody ...

Objective Maternal-fetal RhD antigen incompatibility causes approximately 50% of clinically significant alloimmunization cases. The routine use of prophylactic anti-D immunoglobulin has dramatically reduced hemolytic disease of the fetus and newborn. Recently, fetal RHD genotyping in RhD negative pregnant women has been suggested for appropriate use of anti-D immunoglobulin antenatal prophylaxi...

Anti-D immunoglobulin; BioVue column agglutination test; Quality control; Haemolytic disease; Anti-Rh(D) titration; Rh-factor Abstract The preparation anti-D immunoglobulin is an important therapy for both treatment and protection. Titer of anti-D immunoglobulin preparation is an important factor to determine the dose of treatment. Many methods are used to evaluate the titer of anti-D immunoglo...

AIMS To review our experience of anti-D immunoglobulin for immune thrombocytopenia (ITP) in patients with primary antibody deficiency. METHODS/PATIENTS A retrospective case notes review of four Rhesus positive patients with ITP and primary antibody deficiency, treated with anti-D. Patients were refractory to steroids and high dose intravenous immunoglobulin (IVIG). Two patients were previousl...