Using Salmonella typhimurium strains TA 100 and TA 1535, the mutagenicity and anti-mutagenicity of extracts of several spices were checked. Spices like pepper, pippali, ginger and mustard increased the number of revertants indicating their mutagenic potential. Garlic extract on the other hand was found to inhibit the mutagenicity produced by direct acting mutagens such as N-methyl N'-nitro-N-ni...

Human urine is known to contain substances that strongly inhibit bacterial mutagenicity of aromatic and heterocyclic amines in vitro. The biological relevance of these anti-mutagens was examined by comparing levels of tobacco-related DNA adducts in exfoliated urothelial cells from smokers with the anti-mutagenic activity in corresponding 24-h urine samples. An inverse relationship was found bet...

OBJECTIVES The purpose of this study was to investigate the effect of tomato juice drinking on the antimutagenicity of saliva. METHODS Subjects were 22 healthy male university students. They were divided into tomato group and control group. The tomato group drank tomato juice for 10 days. The anti-mutagenicity of saliva was measured using the umu test. RESULTS In the tomato group, there was...

Cashew (Anacardium occidentale) is a medicinal plant native to Brazil and also yields a nutritious fruit juice. Its large pulpy pseudo-fruit, referred to as the cashew apple, contains high concentrations of vitamin C, carotenoids, phenolic compounds and minerals. Natural and processed cashew apple juice (CAJ/cajuina) are amongst the most popular juices in Brazil, especially in the north-east. B...

Derris brevipes, a common medicinal plant, has multiple uses in traditional system of medicine and in particular it is used as a memory-enhancing agent for centuries. The plant and its extracts have been evaluated for number of activities like anti-inflammatory, cardio-tonic, sedative and neuron-muscular. The plant extract was evaluated for Antimutagenicity and mutagenicity studies in order to ...

OBJECTIVES The purpose of this study was to compare the anti-mutagenicity of Salivette and test-tube sampling saliva. In addition, the relation between the inhibiting and pH-buffering capacities of saliva was investigated. METHODS Subjects were 52 healthy female university students. The collection of saliva samples was carried out using 2 sampling devices; test-tube and Salivette. The anti-mu...

Cymbopogon citratus belonging to the family Gramineae is an herb worldwide known as lemongrass. The prefix ‘lemon’ owes its typical lemon like odor, which mainly due presence of citral, a cyclic monoterpene. fast growing, perennial aromatic grass native South India and Sri Lanka, now widely cultivated in tropical areas America Asia. Freshly cut partially dried leaves are used medicinally source...

A diet rich in fruit and vegetables can be effective in the reduction of oxidative stress, through the antioxidant effects of phytochemicals and other mechanisms. Protection against the carcinogenic effects of chemicals may also be exerted by an enhancement of detoxification and DNA damage repair mechanisms. To investigate a putative effect of flavonoids, a class of polyphenols, on the regulati...