نتایج جستجو برای: Antidiabetic activity

تعداد نتایج: 1140005  

Journal: :iranian journal of pharmaceutical research 0
n yousefian

diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. the management of the blood glucose level is a critical strategy in the control of diabetes complications. inhibitors of carbohydrate hydrolyzing enzymes have been useful as oral hypoglycemic drugs for the control of hyperglycemia especially in patients with type ii disables mellitus. the goal of the present study...

Journal: :مجله بین المللی زیست و زیست پزشکی 0
revathi pitchaipillai postgraduate and research department of pharmacology, chennai medical college hospital & research centre (srm group), tamilnadu dr. mgr medical university, tiruchirapalli, india thirumalaikolundusubramanian ponniah department of medicine, chennai medical college hospital & research centre (srm group), tamilnadu dr. mgr medical university, tiruchirapalli, india

the current epidemic of diabetes indicates the need of proper and effective medications that are limited in their potency to have many side effects. thus, introduction of alternative and complementary medicine is now in picture. the main objective of this study was to analyze the rate of glucose transport across cell membrane in yeast cells system in the presence of the ethanolic extract of bru...

Journal: :iranian journal of pharmaceutical sciences 0
shashikant r. pattan department of pharmaceutical chemistry, pravara rural college of pharmacy, loni, ahemednager, india. prajact kekare department of pharmaceutical chemistry, k. l. e's college of pharmacy belgum, india ashwini patil department of pharmaceutical chemistry, y. b. chavan college of pharmacy aurangabad, india ana nikalje department of pharmaceutical chemistry, y. b. chavan college of pharmacy aurangabad, india bs kittur department of pharmaceutical chemistry, h s k college of pharmacy bagalkot, india

a new series of thiazolidinedione derivatives were synthesized. the structures of these compounds were established by means of ir, 1h-nmr and elemental analysis. all of the compounds were screened for antidiabetic activity on albino rats. most of the compounds showed significant antidiabetic activity when compared with the standard drug glibenclamide.

Journal: :iranian journal of pharmaceutical research 0
nouraddin hosseinzadeh department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran14176, iran. soodeh seraj islamic azad university, shahre rey branch. mohamad ebrahim bakhshi-dezffoli department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran14176, iran. mohammad hasani school of chemistry, college of science, university of tehran, tehran iran. mehdi khoshneviszadeh department of medicinal chemistry, faculty of pharmacy and pharmaceutical sciences research center, tehran university of medical sciences, tehran14176, iran. saeed fallah-bonekohal department of toxicology and pharmacology, faculty of pharmacy and laboratory of toxicology, pharmaceutical sciences research centre, tehran university of medical sciences, tehran 14155-6451, iran.

the complex metabolic syndrome, diabetes mellitus, is a major human health concern in the world and is estimated to affect 300 million people by the year 2025. several drugs such as sulfonylureas and biguanides are presently available to reduce hyperglycemia in diabetes mellitus. these drugs have side effects and thus searching for a new class of compounds is essential to overcome this problems...

Journal: :iranian journal of pharmaceutical sciences 0
varsha tiwari department of pharmacognosy, devsthali vidyapeeth college of pharmacy, lalpur, rudrapur, u.s. nagar uttarakhand (india) 263148 anita singh department of pharmaceutical sciences, bhimtal campus, kumaun university, nainital uttarakhand (india) 263136

in india, the occurrence of diabetes mellitus is on increase and needs to be addressed properly. herbal remedies are considered most suitable for the management of type 2 diabetes due to their traditional acceptability and availability, low costs, and fewer side effects. traditionally bauhinia tomentosa l. (family- fabaceae) is used in the treatment of diabetes in india. aqueous extract and alc...

Journal: :iranian journal of pharmaceutical research 0
aytaç güder giresun university vocational high school of health services

the majority of the antioxidant and antidiabetic activities of fruits are anthocyanins, a group of polyphenolics that are responsible for the color of many fruits, vegetables and flowers. the harvesting time, storage conditions, maturity, extraction steps etc. are very important for the biological activities based on the alteration of chemical composition. the free radical scavenging and antidi...

Journal: :iranian journal of basic medical sciences 0
nilüfer orhan department of pharmacognosy, faculty of pharmacy, gazi university, 06330, etiler, ankara, turkey ülkü gökçen i̇çöz republic of turkey social security institution, 06520, balgat, ankara, turkey levent altun department of pharmacognosy, faculty of pharmacy, ankara university, 06500, tandogan, ankara, turkey mustafa aslan department of pharmacognosy, faculty of pharmacy, gazi university, 06330, etiler, ankara, turkey

objective(s): bidens species are used for their antidiabetic properties traditionally in many countries. aim of this study is to evaluate hypoglycaemic and antidiabetic activity of bidens tripartita extract and to identify its active compounds through bioactivity guided isolation technique. materials and methods: hypoglycaemic effects of b. tripartita extract and its sub-extracts were investiga...

Ana Nikalje Ashwini Patil BS Kittur Shashikant Pattan,

      A new series of thiazolidinedione derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR and elemental analysis. All of the compounds were screened for antidiabetic activity on albino rats. Most of the compounds showed significant antidiabetic activity when compared with the standard drug glibenclamide.

Journal: :the iranian journal of pharmaceutical research 0
nilufer orhan department of pharmacognosy, faculty of pharmacy, gazi university didem deliorman orhan department of pharmacognosy, faculty of pharmacy, gazi university alper gökbulut department of pharmacognosy, faculty of pharmacy, ankara university mustafa aslan department of pharmacognosy, faculty of pharmacy, gazi university fatma ergun department of pharmacognosy, faculty of pharmacy, gazi university

fruit and leaves of junipers are commonly used internally as tea and pounded fruits are eaten to lower blood glucose levels in anatolia. thus, we aimed to evaluate antidiabetic and antioxidant potential and the chemical profile of juniperus foetidissima willd. and j. sabina l. in this study. in-vitro antidiabetic activities of leaf and fruit extracts were examined by their inhibitory activity o...

Levent Altun, Mustafa Aslan, Nilüfer Orhan, Ülkü Gökçen İçöz

Objective(s): Bidens species are used for their antidiabetic properties traditionally in many countries. Aim of this study is to evaluate hypoglycaemic and antidiabetic activity of Bidens tripartita extract and to identify its active compounds through bioactivity guided isolation technique. Materials and Methods: Hypoglycaemic effects of B. tripartita extract and its sub-extracts were investig...

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