amyloid-β (aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in alzheimer’s disease pathology.uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

This paper proposed a parallel automated assembly line system to produce multiple products having multiple autonomous guided vehicles (AGVs). Several assembly lines are configured to produce multiple products in which the technologies of machines are shared among the assembly lines when required. The transportation between the stations in an assembly line (intra assembly line) and among station...

background; work-related musculoskeletal disorders (wmsds) may involve all parts of the body, and have been a worldwide problem. employed women are two to five times more likely to report such problems, and assembly lines suspected to induce more wmsds because of high rate of repetitive motions. methods;the aim of this study to determine the prevalence of wmsds in women workers of an automobile...

The strategic pricing decisions of assembly products in assembly products supply chain are studied in this paper. Firstly, a two-stage assembly products supply chain model is developed. By building Nash game model, the Nash equilibrium solution of pricing strategy of supplier and assemblers is obtained. Next, a union decision model is built to analyze the optimal combination pricing strategy of...

Amyloid-β (Aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in Alzheimer’s disease pathology.Uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. Aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

Considering the present business competitive scenario, the automotive industry is under pressure to achieve higher productivity. A high level of performance and quality standard could be achieved through improving the Overall Equipment Effectiveness (OEE) of the equipment in an automotive industry. Thus, the aim of this study is to investigate the performance measurement through OEE theory in a...

diamondoids are cage-like saturated hydrocarbons consisting of fused cyclohexane rings. thediamondoids family of compounds is one of the best candidates for molecular building blocks (mbbs)in nanotechnology to construct organic nanostructures compared to other mbbs known so far. thechallenge is to find a route for self-assembly of these cage hydrocarbons and their applications in thebottom-up s...

objectives: nowadays, snap-fits are used in the automotive industry as a proper alternative for mechanical joints, cabling joints, and car interior lining joints. due to the special form of these joints, which are assembled manually, the contact area between snap-fits and the worker's fingertips can be too small. this can cause skin pain on the worker's fingertips. therefore, an ergonomic study...

with the growth in customers’ demand diversification, mixed-model u-lines (mmul) have acquired increasing importance in the area of assembly systems. there are generally two different approaches in the literature for balancing such systems. some researchers believe that since the types of models can be very diverse, a balancing approach without simultaneously sequencing of models will not yield...