abstract background: dysfunction of the autonomic nervous system has long been a subject of considerable debate and a large number of studies have disclosed contradictory results. the aim of this study was to compare cerebral vasomotor reactivity in migraine with aura (mwa) patients with migraine without aura (mwo) ones. methods: ten mwa patients (7 females and 3 males mean age: 39.70 years, sd...

conclusions headaches, particularly migraine without aura, are a common occurrence in pregnancy in our population. migraine severity is positively associated with high blood glucose levels. results the headache prevalence during pregnancy was 69% in the women with diabetes and 64% in the women without diabetes. a positive unilateral distribution was observed in 51% of the cases and 36.3% of the...

The study presented here is the first detailed nosographic analysis of migraine aura, diagnosed using the criteria of the International Headache Society, in a sufficiently large sample for statistical analysis. Of 4,000 people, 163 had migraine with aura. Sixty-two had attacks of migraine aura with headache as well as migraine aura without headache, and seven had exclusively migraine aura witho...

Aurora A (AurA) is a major mitotic protein kinase involved in centrosome maturation and spindle assembly. Nucleophosmin/B23 (NPM) is a pleiotropic nucleolar protein involved in a variety of cellular processes including centrosome maturation. In the present study, we report that NPM is a strong activator of AurA kinase activity. NPM and AurA coimmunoprecipitate and colocalize to centrosomes in G...

objective this study was conducted to evaluate the preventive effect of lamotringine on migraine aura and migraine attacks in children, afflicted with classic migraine. material & methods conducted between october 2005 and april 2008 in the neurology clinic of kashani hospital,  shahrekord, this study was a clinical trial, aimed at evaluating the prophylactic effects of lamotringine administere...

OBJECTIVE To determine whether acute migraine treatment outcome is different in migraine with aura compared with migraine without aura. METHODS We examined pooled outcome data for sumatriptan treatment of migraine with and without aura from the sumatriptan/naratriptan aggregate patient database. We also examined similar outcome data for inhaled dihydroergotamine (DHE) from a single, large ran...

BACKGROUND The overexpression of Aurora A kinase (AurA) has been reported in various malignancies, including acute myeloid leukemia (AML). However, the expression of AurA and the effects of AurA inhibition in cancer stem cells are not yet fully understood. We investigated the expression and inhibition of AurA in AML stem cells (CD34(+)/CD38(-)). METHODS Expression of AurA was investigated in ...

Timely activation of Aurora kinase A (AURA, also known as AURKA) is vital for centrosome formation and the progression of mitosis. Nonetheless, it is still unclear if and when other cellular functions are activated by AURA. We report here that Src phosphorylates and activates AURA at T288, and AURA also activates focal adhesion kinase (FAK, also known as PTK2), leading to initiation of cell mov...

the following attempts to discuss the different approaches to privacy adopted by adolf loos and le corbusier, as two of the most influential pioneers of modern architecture. it will be argued that both architects were influenced by the developing technologies of their time, yet they reacted differently to the increasing influence of film and photography on art, architecture and everyday life. t...

INTRODUCTION Persistent migraine aura without headache is an extremely rare condition. The International Headache Society defines various subtypes of migraines, including "persistent migraine aura without infarction" and "typical aura without headache." CASE PRESENTATION We describe the case of a 21-year-old Asian woman with a history of migraine without aura who had (as her first aura episod...