background: b vitamins deficiencies in humans and animals have been known for some time to induce pain and inflammation. these symptoms can be readily alleviated by appropriate administration of vitamins b. the aim of this study was to evaluate opioids requirements and hemodynamic variables and analgesic effect of b vitamins and b vitamins-diclofenac in general anesthesia and post-anesthesia ca...

Introduction: Transplantation of embryonic ventral mesencephalic (VM) dopamine neurons into the striatum is a currently explored therapeutic strategy for treatment of patients with patients with Parkinson's disease (PD). However, this strategy has been limited with poor cell survival, generally ranging from 5-20%. In this study, we investigated the effect of potassium channel blocker of tetr...

Introduction: Studies suggest that ATP-sensitive potassium (KATP) channels are a potential pharmacotherapeutic target for neuroprotection in neurodegenerative diseases. The current study aimed at evaluating the effect of pretreatment with glibenclamide (Glib) and B vitamins supplement on the severity of behavioral symptoms in 6-hydroxydopamine (OHDA)-induced Parkinsonism. Also malondialdehyde (...