The aim of the following research was to formulate benzyl benzoate in emulgel form and to evaluate the release of the medicament from it. Emulgel containing 25% w/w of benzyl benzoate was prepared by addition of a gelling agent; Carbopol 934 to an emulsion using Span 80 as emulsifying agent. The release of benzyl benzoate was determined by Franz diffusion cell using cellulose acetate membrane f...

The total synthesis of two natural phenolglycosides of the family Salicaceae, namely: populoside and 2-(β-d-glucopyranosyloxy)-5-hydroxy benzyl (3-methoxy-4-hydroxy) cinnamoate and nine not found yet in plants acyl derivatives of phenoglycosides: 2-(β-d-glucopyranosyloxy)-benzylcinnamoate, 2-(β-d-glucopyranosyloxy)-benzyl (4-hydroxy) benzoate, 2-(β-d-glucopyranosyloxy)-benzyl (3-methoxy-4-hydro...

We report the first case of an anaphylactic reaction to Reandron 1000 (depot testosterone undecanoate with a castor oil and benzyl benzoate vehicle). While considered to have a favourable safety profile, serious complications such as oil embolism and anaphylaxis can occur. In our patient, skin testing identified benzyl benzoate to be the trigger, with no reaction to castor oil or testosterone u...

Neotropical orchids of subtribes Stanhopeinae and Catasetinae are exclusively pollinated by euglossine bees (Euglossini). This study determines whether orchids present specific combinations and proportions of chemical odors in order to attract a limited subset of euglossine bee species, thereby avoiding hybridization that may result from the attraction of too many pollinators. Chemical baits of...

Ethylene is a gaseous plant hormone involved in many physiological processes including senescence, fruit ripening, and defence. Here the effects of pollination and wound-induced ethylene signals on transcript accumulation of benzoyl CoA:benzyl alcohol/phenylethanol benzoyltransferase (PhBPBT) are shown in Petuniaxhybrida cv. Mitchell 'Diploid' (MD). In petunia, PhBPBT is responsible for the bio...

Alkyldifluorophosphites, ROPF2 (R = ^-substituted benzyl group, neopentyl, 1-adamantyl) have been obtained by a new method, involving reaction of the appropriate alkyl trimethylsilylether, ROSiMe3 with chlorodifluorophosphine, PF2C1. Reactions of these difluorophosphites with platinum(II) complexes of the type [LaPtCla] (L = PEt3, PPI13) led to products such as irans-[L2PtCl(POF2)] and {[p-XC6H...

The enantiomers of XYLNAc (2-N-acetylamino-1,2,4-trideoxy-1,4-iminoxylitol) are prepared from the enantiomers of glucuronolactone; the synthesis of the enantiomers of LYXNAc (2-N-acetylamino-1,2,4-trideoxy-1,4-iminolyxitol) from an L-arabinono-δ-lactone and a D-ribono-δ-lactone is reported. A comparison is made of the inhibition of β-N-acetylhexosaminidases (HexNAcases) and α-N-acetylgalactosam...

In the title compound, C(21)H(18)O(2)S, the central aromatic ring makes dihedral angles of 5.86 (12) and 72.02 (6)° with the rings of the terminal O-benzyl and S-benzyl groups, respectively. The dihedral angle between the peripheral phenyl rings is 66.16 (6)°. In the crystal, mol-ecules are linked by pairs of C-H⋯O hydrogen bonds, forming inversion dimers. These dimers are linked via C-H⋯π inte...

Tandem glycosylation of the 6-O-Fmoc-substituted benzyl orthoester derivative 2a was carried out in moderate yields by electrogenerated acid (EGA). The Fmoc group was effectively removed under mild basic conditions, and the product was submitted to the subsequent glycosylation.