نتایج جستجو برای: Beta-lactamase

تعداد نتایج: 193773  

In the last decades, Extended-Spectrum-β-Lactamases (ESBLs) in gram negative bacilli have appeared as a significant mechanism of resistance to antibiotics. Although resistance to carbapenems is increasing among bacteria, they are still the treatment of choice for serious infections caused by ESBL producers. Therefore, the aim of the present study was to evaluate the effect of ß-lacta...

ژورنال: پژوهش در پزشکی 2015

The study emphasizes the reasons use of beta-lactamase inhibitors in combination with beta-lactam antibiotics. ß-lactam-ß-lactamase inhibitors are currently the most successful strategy for infections caused by extended-spectrum β-lactamase and carbapenemases bacteria.

Introduction: Carbapenems are one of the latest drugs for treatment of threatening infections of Pseudomonas aeruginosa. Resistance to these antibiotics is sometimes caused by carbapnmase class B, such as VIM metallo-beta-lactamase (MBL) that is growing in the communities. The aim of this study was to detect the of metallo-beta-lactamase blaVIM-1 gene among clinical isolates of Pseudomonas aeru...

رستگار لاری, عبدالعزیز, رهبر, محمد, ستارزاده, محبوبه, سلیمان‌زاده مقدم, سمیه, عالی‌نژاد, فرانک, عظیمی, لیلا, محمد‌زاده, مونا,

Background: The increasing use of β-lactam antibiotics in clinics for the treatment of different bacterial infections since early 1980s has led to increased rates of resistant bacteria isolated from patients. One of the problems in the treatment of nosocomial infections is related to resistant bacteria such as Enterobacter cloacae due to cross resistance through extended-spectrum beta-lactamase...

Journal: :jundishapur journal of microbiology 0
sara kooti student research committee, bacteriology and virology department, school of medicine, shiraz university of medical sciences, shiraz, ir iran mohammad motamedifar department of bacteriology and virology, school of medicine, shiraz university of medical sciences, shiraz, ir iran; shiraz hiv/aids research center (sharc), shiraz university of medical sciences, shiraz, ir iran; department of bacteriology and virology, school of medicine, shiraz university of medical sciences, shiraz, ir iran. tel/fax: +98-7132304356 jamal sarvari department of bacteriology and virology, school of medicine, shiraz university of medical sciences, shiraz, ir iran

background the emergence of multidrug-resistant acinetobacter baumannii complicates the therapy of the related infections. hospital isolates of a. baumannii are usually multidrug-resistant. the problem is compounded by increasing resistance to broad-spectrum antibiotics including carbapenems. objectives the aim of this study was to determine antimicrobial susceptibility patterns and distributio...

Journal: :journal of medical bacteriology 0
mohammad mohammadzadeh department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, iran. mahnaz tavakoli department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, iran. abolfazl mohebi department of microbiology, faculty of sciences, islamic azad university, karaj, iran. samad aghayi department of microbiology, faculty of sciences, islamic azad university, karaj, iran.

background :   imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (mbls)-producing strains have been reported to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide. because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all beta-lactams....

Journal: :avicenna journal of clinical microbiology and infection 0
marzieh safari department of microbiology, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran mohammad yousef alikhani department of microbiology, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran; brucellosis research center, hamadan university of medical sciences, hamadan, ir iran; brucellosis research center, hamadan university of medical sciences, hamadan, ir iran. tel: +98-8118380755, fax: +98-8118380130 mohammad reza arabestani department of microbiology, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran; brucellosis research center, hamadan university of medical sciences, hamadan, ir iran reza kamali kakhki department of microbiology, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran rasool jafari department of parasitology and mycology, faculty of medicine, isfahan university of medical sciences, isfahan, ir iran

background pseudomonas aeruginosa is one of the most important agents causing nosocomial infections worldwide. multidrug resistance of isolated bacteria from nosocomial infections makes it difficult and sometimes impossible to treat. objectives the aim of the present study was to investigate the antibiotic resistance and association between blaimp and blavim genes with resistance to meropenem a...

Journal: :archives of trauma research 0
mehrzad sadredinamin department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran ali hashemi department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran hossein goudarzi department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran; department of microbiology, shahid beheshti university of medical sciences, tehran, ir iran. tel: +98-2123872556 samira tarashi department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran neda yousefi nojookambari department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran soroor erfanimanesh department of microbiology, school of medicine, tehran university of medical sciences, tehran, ir iran

background carbapenemes are a good choice for treatment of infections caused by multidrug resistant pseudomonads aeruginosa. the emergence of carbapenem resistance has become a major problem in treatment of this organism especially among immunocompromised patients including burn patients. objectives the aim of this study was to investigate carbapenem-resistance mechanisms among burn patients in...

Journal: :journal of medical bacteriology 0
neda noori department of microbiology, college of basic sciences, karaj branch, islamic azad university, alborz, ir iran. jalil vandyosefi department of microbiology, college of basic sciences, karaj branch, islamic azad university, alborz, ir iran. faeze sabet antimicrobial resistance research center, buali research institute, department of microbiology and virology, medical school, mashhad university of medical sciences, mashhad, ir iran. sara ashrafi antimicrobial resistance research center, buali research institute, department of microbiology and virology, medical school, mashhad university of medical sciences, mashhad, ir iran. kiarash ghazvini antimicrobial resistance research center, buali research institute, department of microbiology and virology, medical school, mashhad university of medical sciences, mashhad, ir iran.

b ackground : the emergence and rapid spread of metallo-beta-lactamase (mbl) producing acinetobacter spp. are of great concern worldwide due to limited treatment options. epidemiologic studies of the causing genes are important for prevention. methods :   in  this  study,  70  imipenem-resistant  acinetobacter  strains  were isolated from health care associated infections. these isolates were s...

Journal: :journal of medical bacteriology 0
mohammad mohammadzadeh 1department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, iran. mahnaz tavakoli 1department of microbiology, school of medicine, shahid beheshti university of medical sciences, tehran, iran. abolfazl mohebi 2department of microbiology, faculty of science, islamic azad university, karaj, iran. samad aghayi 2department of microbiology, faculty of science, islamic azad university, karaj, iran.

background :   imipenem-resistant gram negative bacteria, resulting from metallo-beta-lactamase (mbls)-producing strains have been reported to be among the important causes of nosocomial infections and of serious therapeutic problem worldwide. because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all beta-lactams....

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