Introduction: Theranostic nanoparticles, which integrate both diagnostic and therapeutic capabilities into one nanoagent, has great promise to ablate more effective tumoral tissue by optimizing and real-time monitoring treatment interventions, as well as monitoring therapeutic response to corresponding effect. Multifunctional theranostic nanoagent based on graphene quantum dots...

Pretargeted positron emission tomography (PET) imaging based on bioorthogonal chemical reactions has proven its potential in immunoimaging. It may also have great potential in nanotheranostic applications. Here, we report the first successful pretargeted PET imaging of trans-cyclooctene-modified mesoporous silicon nanoparticles, using 18F-labeled tetrazine as a tracer. The inverse electron-dema...

Mn-based nanoparticles have been regarded as a new class of probes for magnetic resonance imaging (MRI), but their low relaxivity is the major obstacle for applications in vivo. Herein, we designed and constructed a multifunctional nanotheranostic (FA-Mn3O4@PDA@PEG) for MRI guided combinatorial chemo-/photothermal therapy (PTT) for cancer. The ultrahigh relaxivity of 14.47 mM-1 s-1 makes the na...

Globally, cancer is one of the deadliest diseases, needing a meticulous diagnosis and targeted treatment plan to achieve an initial prognosis, followed by precision optimization in treatment. Nonselective targeting, difficulty accurately monitoring end-results, serious drug side-effects, severity disease resulting metastasis are key flaws traditional techniques. Nanotechnology nanoparticles pos...

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. New diagnostic and therapeutic strategies are needed to mitigate this public health issue. Advances in nanotechnology have generated innovative strategies for diagnosis and therapy in a variety of diseases, foremost in cancer. Based on these studies, a novel concept referred to as nanomedical theranostics, o...

Since the last decade, polymer-drug conjugate (PDC) approach has emerged as one of most promising drug-delivery technologies owing to several benefits like circumventing premature drug release, offering controlled and targeted delivery, improving stability, safety, kinetics conjugated drugs, so forth. In recent years, PDC technology advanced with objective further enhance treatment outcomes by ...

The review highlights the nanotheranostic agents prove to be highly efficient in generating theragnosis overcoming deficiencies noted with conventional diagnostic and therapeutic used for cancers.