background: cholangiocarcinoma is an invasive biliary malignancy with poor prognosis. diagnostic accuracy of conventional methods is low which is mainly due to the specific anatomy of the disease. the aim of this study was to evaluate the diagnostic value of biochemical profile and tumor marker of the bile in patients with malignant cholestasis compared to that of choledocholithiasis. methods: ...

the aim of the study was to explore the mechanisms underlying the association of birth weight with later body mass index (bmi) from the biochemical markers related to metabolism and the apa i polymorphism in igf-ii gene.a total of 300 children were selected randomly from the macrosomia birth cohort in wuxi, china. the height and weight were measured and blood samples were collected. plasma conc...

Unusual protein containing a high level of histidine and eight other amino acids (i.e. glycine, alanine, serine, threonine, arginine, glutamic acid, aspartic acid and tyrosine) is localized in the epidermal granular cell layer of the newborn rat. I t appears that the formation of "histidine-protein" is a step in the sequence of epidermal differentiation terminating in keratinization. This paper...

We have measured intracellular brain pH in vivo in 42 boys and found a significant correlation between this biochemical parameter and samples of intelligent behaviour. To the best of our knowledge this is the first reported relation between a biochemical marker which is within normal physiological values and intellectual ability. pH is one of the most accurate parameters that can be measured by...