Background: Biofilm formation by Pseudomonas aeruginosa is a serious concern in treatment of diseases and medical industries. Natural products that originate in plants can influence microbial biofilm formation. The effect of ethyl acetate, methanol and water- methanol extracts of Quercus brantii on biofilm formation and biofilm disruption of P. aeruginosa were investigated in this study. Methods...

conclusions minimum biofilm eradication values of ciprofloxacin obtained in the study are close to the values of the minimal inhibition concentration (mic). results all tested strains formed a biofilm. a value of 1.0 μg/ml ciprofloxacin is mbe50 for the strains of both tested species. an mbe90 value of ciprofloxacin for isolates of p. vulgaris was 2 μg/ml and for p. mirabilis was 512 μg/ml. mat...

Objectives:Biofilms are communities of bacteria attached to surfaces through an external polymeric substances matrix. In the meantime, Acinetobacterbaumannii is the predominant species related to nosocomial infections. In the present study, the effect of silver nanoparticles alone and in combination with biocides and imipenem against planktonic and biofilms of A. baumannii was assessed.  Materi...

objectives:biofilms are communities of bacteria attached to surfaces through an external polymeric substances matrix. in the meantime, acinetobacterbaumannii is the predominant species related to nosocomial infections. in the present study, the effect of silver nanoparticles alone and in combination with biocides and imipenem against planktonic and biofilms of a. baumannii was assessed.  materi...

The aim of the study was to examine the antibiofilm activity of selected essential oils (EO): Lavandula angustifblia (LEO), Melaleuca alternifolia (TTO), Melissa officinalis (MEO) and some of their major constituents: linalool, linalyl acetate, alpha-terpineol, terpinen-4-ol. Biofilms were formed by Staphylococcus aureus ATCC 29213 and Escherichia coli NCTC 8196 on the surface of medical biomat...

Development of biofilm is a key mechanism involved in Staphylococcus epidermidis virulence during device-associated infections. We aimed to investigate antibiofilm formation and mature biofilm eradication ability of ethanol and water extracts of Thai traditional herbal recipes including THR-SK004, THR-SK010, and THR-SK011 against S. epidermidis. A biofilm forming reference strain, S. epidermidi...

Objective(s): Staphylococcus epidermidis is a common cause of medical device-associated infections due to biofilm formation, and its elimination is extremely challenging. Although rifampin efficacy against S. epidermidis biofilms has been confirmed, its use as a single agent may lead to resistance. As such, it is assumed that the combination of rifampin and N-acetylcysteine (NAC) could exert ad...

INTRODUCTION Antimicrobial activity on biofilms depends on their molecular size, positive charges, permeability coefficient, and bactericidal activity. Vancomycin is the primary choice for methicillin-resistant Staphylococcus aureus (MRSA) infection treatment; rifampicin has interesting antibiofilm properties, but its effectivity remains poorly defined. METHODS Rifampicin activity alone and i...

Correspondence to: Dong Ho Lee Department of Internal Medicine, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 463-707, Korea Tel: +82-31-787-7006, Fax: +82-31-787-4051, E-mail: [email protected] pISSN 1976-2283 eISSN 2005-1212 http://dx.doi.org/10.5009/gnl15117 Adjuvant agents to the Helicobacter pylori eradication regimen have been continuously stud...

Background: Pseudomonas aeruginosa biofilm is one of the problems in antibiotic treatment of infections. Nanomedicines such as chitosan can carry multiple drugs and improve the therapeutic effects of antibiotics. Objectives: The study aimed to synthesis and characterization of ciprofloxacin loaded chitosan nanoparticle for eradication biofilm of P. aeroginosa. Methods: Cipro-CS microparticles...