Introduction: Transfusion of irradiated blood is recommended by the guidelines for cardiosurgery, cancer surgery, severe trauma and congenital immune deficient recipients. To prevent post- transfusion graft-versus-host disease (PT-GVHD), blood cells may be irradiated by gamma rays. The absorbed dose range for blood irradiation is typically 15 to 50 Gy. As the assurance that blo...

Spectrophotometric measurements of the Fricke–gelatin–xylenol orange (FGX) gel dosimeter demonstrated reproducible linear dose response up to 25Gy. However, oxidation processes continue post-irradiation, affecting the response of this dosimetry system. Additional oxygenation during preparation increases the sensitivity of the gel but does not improve the auto-oxidation stability of the dosimete...

Gafchromic films are increasingly being used for dosimetry in medical and industrial applications of ionizing radiation because of their favorable characteristics such as self developing in nature, easy to handle, dose rate independent response, insensitivity to normal room lights, high resolution and insensitivity to variation in the environment conditions. The dosimetry measurements using Gaf...

Fricke solution has a wide range of applications as radiation detector and dosimetry. It is particularly appreciated in terms of relevant comparative advantages, like tissue-equivalence when prepared in aqueous media like gel matrix, continuous mapping capability, independence of dose rate and incident direction, as well as linear dose response. This work presents the development and characteri...

The innovation of adding a gel matrix to the traditional Fricke dosimeter to stabilize geometric information established the field of gel dosimetry for radiation therapy. A discussion of Fricke gels provides an overview of the issues that determine the dose response of all gel dosimeters in general. In this paper we review some of the features of Fricke systems to illustrate these issues and, i...

Currently, the use of blood irradiation for inactivating pathogenic microbes in infected blood products and preventing graft-versus-host disease (GVHD) in immune suppressed patients is greater than ever before. In these systems, dose distribution and uniformity are two important concepts that should be checked. In this study, dosimetry of the gamma chamber blood irradiator model Gammacell 3000 ...

Radiation dosimetry by Fricke gel was largely used, generally focused and optimized for radiotherapy applications therefore involving relative high dose levels. Fricke gel dosimetry has several advantages, like dose rate and LET almost independence, 3D mapping, among other. This work presents a novel Fricke gel dosimeter optimized for low dose levels. Several chemical composition were studied v...

Irradiation of whole blood and blood components before transfusion is currently the only accepted method to prevent Transfusion-Associated Graft-Versus-Host-Disease (TA-GVHD). However, choosing the appropriate technique to determine the dosimetric parameters associated with blood irradiation remains an issue. We propose a dosimetric system based on the standard Fricke Xylenol Gel (FXG) dosimete...

background: the compositions of ferrous sulphate, agarose and xylenol orange dye (fax) and ferrous sulphate, gelatin and xylenol orange dye (fgx) in solution of distilled water and sulphuric acid are two tissue-equivalent gel dosimeters. ionizing radiation causes oxidation of fe2+ ion to fe3+ ions which diffuse through the gel matrix and blur the image of absorbed dose over a period of hours af...

Fricke gel dosimetry is a valuable method for in-phantom dose measurements in complex irradiation modalities like IMRT and BNCT. Implementation of this dosimetry technique requires dedicated instruments capable of measuring and further analysis immediately in situ at the radiation facility. This work presents a novel and integral dosimetry system aimed to attain portability requirements. The me...