preparations of platelet concentrates (pcs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (pmps) with high coagulant activity that may change platelet efficacy and safety issues. high shear stress could cause shedding of pmps from the platelet plasma membrane, platelet aggregation, and activation of the co...

blood transfusion centers are under considerable pressure to produce platelet concentrates with high quality and safety due to the short shelf life of 3-5 days as well as possible bacterial and viral contaminations. for a variety of reasons, many europeans have changed their methods of component production from whole blood using the north american standard platelet-rich plasma method to the buf...

introduction: the aim of this study was to evaluate the neutrophil-to-lymphocyte ratio (nlr), platelet-to-lymphocyte ratio (plr), and mean platelet volume (mpv) in patients with recurrent aphthous stomatitis (ras).   materials and methods: eighty patients who were diagnosed with ras between january 2014 and january 2016 were included in this study. eighty age- and gender-matched healthy subject...

background: activated platelets shed microparticles (mps) in vivo and certainly in vitro under storage. like platelets, platelet-derived mps contribute to hemostatic and inflammatory responses. we sought to determine the interactions between platelet mps and peripheral b lymphocytes in the healthy blood circulation to propose a possible role for platelet mps in the functioning of b cells.   mat...

Background: Platelet preparations have been used for a wide variety of clinical applications such as hemorrhage, tissue engineering and cellular therapy. Platelet concentrates can be prepared by the apheresis method or from the whole blood using the Buffy-coat or Platelet-rich plasma methods. The purpose of this study was to compare four variations of platelet-rich plasma method based on double...

Blood transfusion centers are under considerable pressure to produce platelet concentrates with high quality and safety due to the short shelf life of 3-5 days as well as possible bacterial and viral contaminations. For a variety of reasons, many Europeans have changed their methods of component production from whole blood using the North American standard platelet-rich plasma method to the buf...

Preparations of platelet concentrates (PCs) that are stored under blood bank conditions and used for transfusion purposes, appear to be enriched in platelet derived-microparticles (PMPs) with high coagulant activity that may change platelet efficacy and safety issues. High shear stress could cause shedding of PMPs from the platelet plasma membrane, platelet aggregation, and activation of the co...

objectives: this study focuses on the hematological parameters change and age in radiation field workers. the study aimed to identify the effect of radiation on hematological parameters and their relation to age and duration of the experience in radiation field workers. material and methods: this study was conducted in the physiology research center in collaboration with thalassemia and hemogl...

background: platelet preparations have been used for a wide variety of clinical applications such as hemorrhage, tissue engineering and cellular therapy. platelet concentrates can be prepared by the apheresis method or from the whole blood using the buffy-coat or platelet-rich plasma methods. the purpose of this study was to compare four variations of platelet-rich plasma method based on double...