in this research, the magnetite nanoparticles (fe304) were prepared by coprecipitation of fe3+ andfe solution in alkaline medium. two kinds of surfactants, cetyl tri methyl ammonium bromide(ctab) and cetyl pyridinum chloride (cpc) were used in the synthesis. fe304 nanoparticles werecoated with human serum albumin (hsa) and bovine serum albumin (bsa). characteristics ofcoated magnetic nanopartic...

background: progress in the field of biology and biochemistry has led to the discovery of numerous bioactive peptides and proteins in the last few decades. delivery of therapeutic proteins/peptides has received a considerable amount of attention in recent years. methods: in this study, a two-step desolvation method was used to produce biodegradable hydrophilic gelatin nanoparticles (gnp) as a d...

In this research, the Magnetite nanoparticles (Fe304) were prepared by coprecipitation of Fe3+ andFE solution in alkaline medium. Two kinds of surfactants, cetyl tri methyl ammonium bromide(CTAB) and cetyl pyridinum chloride (CPC) were used in the synthesis. Fe304 Nanoparticles werecoated with human serum albumin (HSA) and bovine serum albumin (BSA). Characteristics ofcoated magnetic nanopartic...

objective(s): over the past two decades, considerable interest has been focused on utilizing biocompatible magnetic nanoparticles (mnps) for biomedical applications. in this study, production of human serum albumin (hsa) nanoparticles using desolvation technique that were simultaneous loaded with high amounts of superparamagnetic iron oxide nanoparticles (spions) and 5-flourouracil (5-fu) was i...

BACKGROUND Colon cancer is one of the major causes of death in the Western world. Early detection significantly improves long-term survival for patients with the disease. Near- infrared (NIR) fluorescent nanoparticles hold great promise as contrast agents for tumor detection. NIR offers several advantages for bioimaging compared with fluorescence in the visible spectrum, ie, lower autofluoresce...

Objective(s): Cancer diagnosis in its early stages of progress, can enhance the efficiency of treatment utilizing conventional therapy methods. Non-biocompatibility of iron oxide nanoparticles (IONPs) has made a big challenge against their usage as a contrast agent. Efficient coverage by biomolecules such as albumin can be a solution to overcome this problem. Herein, albumin-coated IONPs were p...

Objective(s): Over the past two decades, considerable interest has been focused on utilizing biocompatible magnetic nanoparticles (MNPs) for biomedical applications. In this study, production of human serum albumin (HSA) nanoparticles using desolvation technique that were simultaneous loaded with high amounts of superparamagnetic iron oxide nanoparticles (SPIONs) and 5-flourouracil (5-FU) was i...

We report here on the utilization of poly(lauryl methacrylate)-b-poly(oligo ethylene glycol methacrylate) (PLMA-b-POEGMA) amphiphilic block copolymers, which form compound micelles in aqueous solutions, as nanocarriers for the encapsulation of either magnetic iron oxide nanoparticles or iron oxide nanoparticles, and the model hydrophobic drug indomethacin in the their hydrophobic core. The mixe...

BACKGROUND Superparamagnetic iron oxide nanoparticles have been used in clinical applications as a diagnostic contrasting agent. Previous studies showed that iron oxide nanoparticles deposited in the liver and spleen after systemic administration. The present study investigated the effect of iron oxide nanoparticles on antigen-specific immune responses in mice sensitized with the T cell-depende...

background and aims: some nanoparticles can be used in immunoassays to increase sensitivity. this study aimed to evaluate a novel nano-immunoassay based on bovine serum albumin nanoparticles (bsa nps). materials and methods: at first, the nanostructure was synthesized, and then applied as a tag in the nano-immunoassay. then the concentration of β-subunit of human chorionic gonadotropin (βhcg) i...