Después de años de un continuado crecimiento muy por encima el de nuestro producto interior bruto, el gasto sanitario empieza mostrar inequívocamente su frenada. Las alegrías de su pasado umento se tornan en tristeza y decaimiento, con una verosímil endencia a ir a menos. Es comprensible que la situación no suscite legría, pero no deja de extrañar la generalizada preocupación por l «mal color» ...

The government has decided that its monetarist policy should extend into the management of the NHS. In 'Working for Patients' the government outlines its policy which, in essence, is a blueprint for controlling the ever-escalating costs of health care. It seeks to exert this control by a two pronged budgetary approach, one at regional level and one at the basic provider level. The regional budg...

The objective of this study was to estimate the net cost of arsenic trioxide (ATO) added to all-trans retinoic acid (ATRA) compared to ATRA plus chemotherapy when used in first-line acute promyelocytic leukemia (APL) treatment for low to intermediate risk patients from the perspective of the overall Italian healthcare systemA Markov model was developed with 3 health states: stable disease, dise...

OBJECTIVE To evaluate the economic impact of buprenorphine/naloxone (B/N) as an agonist opioid treatment for opiate dependence. METHODS A budgetary impact analysis model was designed to calculate the annual costs (drugs and associated costs) to the Spanish National Healthcare System of methadone versus B/N. Data for the model were obtained from official databases and expert panel opinion. R...

Ferric citrate (FC) has demonstrated efficacy as a phosphate binder and reduces the requirements for erythropoiesis-stimulating agents (ESAs) and intravenous (IV) iron in dialysis patients. We developed a net budgetary impact model to evaluate FC vs. other phosphate binders from the vantage of a large dialysis provider. We used a Markov microsimulation model to simulate mutually referential lon...