نتایج جستجو برای: Bupivacaine

تعداد نتایج: 5472  

Journal: :anesthesiology and pain medicine 0
seyed abbas hosseini jahromi department of anesthesiology, qazvin university of medical sciences, shahid rajaee hospital, qazvin, iran sadegh sadeghi poor department of surgery, qazvin university of medical sciences, qazvin, iran seyedeh masoumeh hosseini valami department of anesthesiology, qazvin university of medical sciences, shahid rajaee hospital, qazvin, iran; department of anesthesiology, qazvin university of medical sciences, shahid rajaee hospital, qazvin, iran. tel: +98-283335800, fax: +98-2813344812 amir javadi department of social medicine, qazvin university of medical sciences, qazvin, iran

conclusions patients in the bupivacaine infiltration and caudal block groups had less postoperative pain than those in the acetaminophen group and received lower amount of meperidine. we concluded that in children, bupivacaine infiltration and caudal block with bupivacaine produce better analgesia than suppository acetaminophen. it seems that bupivacaine infiltration is better than caudal block...

2010
Mai Mukozawa Ko Takakura Maki Mizogami

Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(-)- and R(+)-bupivacaine. Methods. We performed functional examinations using isolated intact thoracic aortic rings from male Wistar rats. Changes in ring tension produced by S(-)-, R(+)-, or ra...

Journal: :Turkish journal of anaesthesiology and reanimation 2016
Ayşe Ünal Düzlü Berrin Günaydın Murat Kadir Şüküroğlu İsmail Tuncer Değim

OBJECTIVE We aimed to compare the possible controlled release profile of multilamellar liposomal bupivacaine formulations with non-liposomal forms in artificial cerebrospinal fluid (CSF) under in vitro conditions. METHODS Liposome formulations were prepared using a dry-film hydration method. Then, an artificial CSF-buffered solution was prepared. Bupivacaine base with liposomal bupivacaine ba...

2016
Jeffrey Gadsden William J. Long

BACKGROUND Liposome bupivacaine is a prolonged-release bupivacaine formulation indicated for single-dose administration into the surgical site to produce postsurgical analgesia. METHODS An overview of time to onset of analgesia observed with liposome bupivacaine in human studies is provided, as well as a summary of data from pharmacokinetic studies including those that assessed pharmacokineti...

Journal: :Anesthesia and analgesia 2011
Marcio G Kiuchi Gisele Zapata-Sudo Margarete M Trachez Douglas Ririe Roberto T Sudo

BACKGROUND The susceptibility of children and newborns to cardiotoxicity from racemic bupivacaine, RS(±)-bupivacaine, is controversial. Some studies indicate that newborns can sustain higher bupivacaine plasma levels than adults, without severe toxicity. In this study, we compared the influence of age on cardiotoxicity from RS(±)-bupivacaine and S(-)-bupivacaine in rats. The effects of these lo...

2015
Girish P Joshi Gary Patou Vladimir Kharitonov

BACKGROUND This report presents results from four preclinical studies evaluating safety and pharmacokinetics (PKs) of liposome bupivacaine following intravascular (intravenous [IV], intra-arterial [IA]), epidural, and intrathecal administration in dogs. METHODS Intravascular administration was initially tested in a pilot study to determine maximum tolerated doses, and then in an expanded stud...

Journal: :journal of family and reproductive health 0
azin alavi reproductive health research center, shahid beheshti university of medical sciences and health services, tehran, iran saghar salehpour reproductive health research center, shahid beheshti university of medical sciences and health services, tehran, iran mahnaz narimani department of anesthesiology and pain research institue, shahid beheshti university of medical sciences and health services, tehran, iran

objective: this study investigated the efficacy of bupivacaine wound infusion for pain control and opioid sparing effect after cesarean delivery. materials and methods: we conducted a randomized double blind, placebo controlled clinical trial on 60 parturients undergoing cesarean section at a university hospital in tehran. patients were randomized to receive a pump infusion system that was fill...

Journal: :jundishapur journal of natural pharmaceutical products 0
nader saki hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran neda alsadat jasemi hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran lila mashali hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran maziar baikpour hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran soheila nikakhlagh hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; hearing and speech research centre, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-9161111395, fax: +98-6132921838 hasan abshirini hearing and speech research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

conclusions considering that tonsillectomy is one of the most common surgeries in children and produces a lot of pain, using a low risk medicine such as bupivacaine to recover child as soon as possible seems reasonable. results patients aged 4 to 13 years. the amount of postoperative pain was obviously less in the bupivacaine group than the other group. the mean time of postoperative fluid inta...

Journal: Surgery and Trauma 2014
Amene Sabzi Sarvestani, Shahram Amini,

 Introduction: shorter hospital stay and less pain in comparison to open surgery considered to be major benefits for laparoscopic cholecystectomy. We compared the effect of intraperitoneal hydrocortisone plus bupivacaine with bupivacaine alone on pain relief following laparoscopic cholecystectomy.  Methods: Sixty two patients participated in this double-blind, randomized clinical trial. Pati...

Journal: :Anesthesiology 2002
Anthony E Pickering Hidefumi Waki P Max Headley Julian F R Paton

BACKGROUND The inadvertent systemic administration of bupivacaine has been associated with fatal cardiovascular collapse. Systemic bupivacaine may affect neural control of the cardiovascular system in addition to having toxic actions on the heart. The study tested the hypothesis that systemic bupivacaine has toxic effects on brainstem cardiorespiratory control. METHODS The working heart-brain...

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