Contributor’s Comment: The liver demonstrates multifocal, coalescing hepatic necrosis. The necrotic hepatocytes are eosinophilic and have indistinct nuclei. Karyorrhectic nuclei are in the necrotic areas. Neutrophils and lymphocytes infiltrate the necrotic regions. Also evident are syncytial cells. Mouse hepatitis virus belongs to the family Coronaviridae and genus Coronavirus. It is a pleomorp...