objective(s):human cytomegalovirus (cmv), a double-strand dna herpesvirus, can be transmitted via blood transfusion which is especially important for immunocompromised recipients and can cause a fatal infection. cmv seroprevalence in iran was studied on blood donors, healthy subjects, and some patients. highly variable rates were detected. the purpose of this study was to review cmv seroprevale...

cytomegaloviurs (cmv) is the most frequent cause of congenital infection in humans. in various parts of the world the prevalence of antibodies to cmv ranges from 40-100%. the prevalence of primary infection with cmv in pregnant iranian women and risk of congenital cmv infection in their neonates are unknown. to determine the prevalence of cmv infection in primiparous pregnant (youner) women and...

Cytomegalovirus (CMV) causes clinical issues primarily in immune-suppressed conditions. CMV-associated anterior uveitis (CMV-AU) is a notable new disease entity manifesting recurrent ocular inflammation immunocompetent individuals. As patient demographics indicated contributions from genetic background and immunosenescence as possible underlying pathological mechanisms, we analyzed the immunoge...

Aim. Screening of vegetable crops for mixed viral infections caused by 8 viruses, and evaluation relative share different combinations pathogens using serological methods plant virus diagnostics. Methods. Double-antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA) was performed detection antigens. Results. For this study, the samples from plants with virus-like symptoms were collecte...

BACKGROUND Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection. CASE PRESENTATION Here we report a full-term, formula-fed infant who developed a severe cytomegalovirus anaemia and colitis when aged 2 months. CONCLUSION Even if the molecular identity betw...

Objective To characterize T-cell receptors (TCRs) and identify target epitopes in multiple sclerosis (MS). Methods Peripheral blood mononuclear cells were obtained from 39 MS patients 19 healthy controls (HCs). TCR repertoires for α/β/δ/γ chains, diversity, V/J usage determined by next-generation sequencing. β chain compared with affectation status using a novel clustering method, Grouping of L...

Cytomegalovirus (CMV) infection in immunocompetent adults is usually asymptomatic, but results lifelong latency. Infection occurring congenitally or immunodeficiency can lead to cognitive impairment. We aimed investigate the associations between CMV exposure and intelligence quotient (IQ) patients with schizophrenia spectrum disorders (SZS), bipolar (BDS) healthy controls (HC). immunoglobulin G...

Cytomegalovirus (CMV) is the leading cause of viral-associated congenital infections. Moreover, it can also be acquired. Between 50 to 80 percent of the world’s population is seropositive for CMV and most clinical disease occurs in individuals previously infected with CMV. Rarely, serious CMV infection has occurred in individuals with healthy immune system. In contrast to immunocompetent patien...

cytomegalovirus (cmv) is a widespread pathogen that is found in milk, saliva, urine, cervical secretions, and semen fluid. it is supposed that cmv is a risk factor for breast cancer. the aim of this study was to determine the frequency of cmv among benign and malignant breast tumors. paraffin embedded breast carcinoma (n=24) and fibroadenoma (n=24) samples were collected from toos and firoozgar...

Introduction Postnatal cytomegalovirus (CMV) infection of immunocompetent hosts is usually inapparent but typically results in lifelong latency. Congenital CMV infections as well patients with immunodeficiencies have been linked to major cerebellar pathology. Patients severe mental illness repeatedly found smaller cerebellum, and they may be particularly susceptible infections. Finally, both an...