objective(s):human cytomegalovirus (cmv), a double-strand dna herpesvirus, can be transmitted via blood transfusion which is especially important for immunocompromised recipients and can cause a fatal infection. cmv seroprevalence in iran was studied on blood donors, healthy subjects, and some patients. highly variable rates were detected. the purpose of this study was to review cmv seroprevale...

background : cytomegalovirus (cmv) is the most common cause of congenital infection, with increased morbidity and mortality at birth. the risk of intrauterine infection largely depends on the time of maternal infection during pregnancy. currently, no national screening test for cmv infection is available during pregnancy in iran. the aim of this study was to determine the seroprevalence of cmv ...

Background Beta-thalassemia patients receive blood products from blood transfusion centers repeatedly. Blood transfusion can transmit Cytomegalovirus (CMV) and Toxoplasma gondii. The aim of this study was serological evaluation of these two infectious agents in thalassemia patients. Materials and Methods In a cross-sectional study, the enzymelinked immunosorbent assay (ELISA) testing was pe...

The measurement of the avidity of cytomegalovirus (CMV) immunoglobulin G (IgG) antibodies has been shown by several investigators to be useful in identifying and excluding primary CMV infections in pregnant women. In this work, we examined the diagnostic utility of reflex testing of CMV IgM-positive specimens from pregnant women by using a CMV IgG avidity assay. The utility of this approach was...

The diagnosis of congenital cytomegalovirus (CMV) infection is often accomplished by the detection of circulating antibody directed against CMV. We devised a method for measuring CMV-specific immunoglobulin M (IgM) based on the isolation of IgM antibody by reaction with a solid phase coated with antihuman IgM. The determination of IgM antibody specific for CMV was accomplished by the subsequent...

conclusion we concluded that cmv is the most common cause of intrauterine infection in infants aged less than 6 months as compared to the healthy ones. we prefer, at least in our country, to consider seropositive (cmv-igm) infants suspected of intrauterine infection (less than 6 months) as congenital form. to arrest the natural progression of congenital cmv, we recommend prolonged course of ora...

To assess the problem of CMV infection in pregnant women in Sohag community and to determine the risk of congenital CMV infection. The study was performed on 900 pregnant women residing in Sohag, during the period from June, 2006 till January 2010. Detection of CMV antibodies (IgM and IgG) was carried out using microparticle enzyme immunoassay. Women proved positive (+ve) for CMV IgM or IgG ant...

A new microparticle enzyme immunoassay (MEIA), the Cytomegalovirus (CMV) Immunoglobulin M (IgM) test, was developed on the Abbott AxSYM analyzer. This test uses recombinant CMV antigens derived from portions of four structural and nonstructural proteins of CMV: pUL32 (pp150), pUL44 (pp52), pUL83 (pp65), and pUL80a (pp38). A total of 1, 608 specimens from random volunteer blood donors (n = 300),...

BACKGROUND Cytomegalovirus (CMV) is the most common cause of congenital infection, with increased morbidity and mortality at birth. The risk of intrauterine infection largely depends on the time of maternal infection during pregnancy. Currently, no national screening test for CMV infection is available during pregnancy in Iran. The aim of this study was to determine the seroprevalence of CMV in...

Recently, using polymerase chain reaction (PCR) technique, the DNA of cytomegalovirus was detected from depigmented white patches in patients with vitiligo. The reactivation of infection and occasional anti-CMV IgM circulating among patients infected by cytomegalovirus has been reported for years. We have studied 26 patients with clinical signs and symptoms of vitiligo, some of whom had a ...