نتایج جستجو برای: Calcium/calmodulin-dependent kinase II

تعداد نتایج: 1374314  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Heather L Hinds Ivan Goussakov Kazu Nakazawa Susumu Tonegawa Vadim Y Bolshakov

A significant fraction of the total calciumcalmodulin-dependent protein kinase II (CaMKII) activity in neurons is associated with synaptic connections and is present in nerve terminals, thus suggesting a role for CaMKII in neurotransmitter release. To determine whether CaMKII regulates neurotransmitter release, we generated and analyzed knockout mice in which the dominant alpha-isoform of CaMKI...

Journal: :iranian journal of basic medical sciences 0
hadi razavinikoo department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran hoorieh soleimanjahi department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran gholamreza haqshenas department of microbiology, faculty of medicine, nursing & health sciences, school of biomedical sciences, monash university, melbourne, victoria, australia taravat bamdad department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran ali ali teimoori department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran zahra goodarzi department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran

objective(s): the rotavirus nonstructural protein 4 (nsp4) is responsible for the increase in cytoplasmic calcium concentration through a phospholipase c-dependent and phospholipase c-independent pathways in infected cells. it is shown that increasing of intracellular calcium concentration in rotavirus infected cells is associated with the activation of some members of protein kinases family su...

Ali Ali Teimoori Gholamreza Haqshenas Hadi Razavinikoo Hoorieh Soleimanjahi, Taravat Bamdad, Zahra Goodarzi,

Objective(s): The rotavirus nonstructural protein 4 (NSP4) is responsible for the increase in cytoplasmic calcium concentration through a phospholipase C-dependent and phospholipase C-independent pathways in infected cells. It is shown that increasing of intracellular calcium concentration in rotavirus infected cells is associated with the activation of some members of protein kinases family su...

2012
PIERRE PERRUCHET BÉNÉDICTE POULIN-CHARRONNAT SÉBASTIEN PACTON

loss in mouse models of neurodegeneration. Behavior Genetics, 37, 79–100. Galton, F. (1869). Hereditary genius: An inquiry into its laws and consequences. London: Macmillan. Shors, T. J., & Matzel, L. D. (1997). Long-term potentiation: What’s learning got to do with it? The Behavioral and Brain Sciences, 20, 597–655. Silva, A. J., Stevens, C. F., Tonegawa, S., & Wang, Y. (1992). Deficient hippo...

2017
Meenakshi Tiwari Shail K. Chaube

| Several signal molecules modulate the physiology of mammalian oocytes. Changes in the level of various signal molecules and their downstream impact on maturation promoting factor (MPF) during the achievement of meiotic competency remain ill understood. Therefore, the present study aimed to analyze levels of various signal molecules and MPF during the achievement of meiotic competency in rat o...

2005
Joanna L. Jankowsky Hilda H. Slunt Victoria Gonzales Alena V. Savonenko Jason C. Wen Nancy A. Jenkins Linda H. Younkin Henry A. Lester Steven G. Younkin David R. Borchelt

Abbreviations: Ab, amyloid-b; AD, Alzheimer disease; APLP, amyloid precursor–like protein; APP, amyloid precursor protein; CaMKIIa, calciumcalmodulin kinase IIa; dox, doxycycline; FA, formic acid; GFAP, glial fibrillary acidic protein; mo/ huAPP695, mouse APP with a humanized Ab domain; PBS, phosphate-buffered saline; SDS, sodium dodecyl sulfate; swe/ind, Swedish/Indiana; tTA, tetracycline tran...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پزشکی 1391

مطالعات انجام شده روی مکانیسمهای تکوینی و تکاملی گلبولهای قرمز منجر به دستیابی بشر به مفاهیم پایه و مهمی در ارتباط با مکانیسمهای عمومی تنظیم بیان ژن وشکل گیری بافتها شده است. تمایز اختصاصی به رده ارتیروئید و هر رده دیگری، شدیداً وابسته به تنظیم در سطح بیان ژن و فاکتورهای کنترلی خاص نظیر سیتوکین ها، فاکتورهای نسخه برداری ویژه، عناصر کنترل کننده چرخه سلولی، تکثیر،آپوپتوز و عناصر سیگنالینگ داخل سلو...

2010
Elvira Salas David León Navarro Jesús Sánchez-Nogueiro Patricia Marín-García María Teresa Miras-Portugal DAVID LEÓN NAVARRO

ATP elicits Ca transients in cultured cerebellar granule neurons acting through specific ionotropic (P2X) and metabotropic (P2Y) purinergic receptors. In these neurons, application of L-Glutamate (L-Glu) immediately before ATP induced a prolonged reduction of ATP-mediated responses that remains at least 5 minutes after L-Glu wash out. alpha-amino-3-hydro-5-methyl-4-isoxazolpropionic acid (AMPA)...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید