.......................................................................................................... xi 1. ENDOTHELIUM-DEPENDENT VASODILATION: A REViEW ..................................... 1 What is the Nature of the Cholinergic, Endothelium-Dependent Response? 1 Endothelium-Derived Relaxing Factor ................................................. 2 Influence of Contractile Agent and Ton...

Background: Chemical activation is the most frequently method for artificial oocyte activation, resultant in high fertilization rates. The aim of this prospective randomized controlled study is evaluating the effect of calcium ionophore on fertilization and pregnancy rate in infertile men suffering from teratoospermia. Materials and Methods: 38 women with teratoospermic partner were divided int...

lonophore-based ion-selective optical nanosensors have been explored for a number of years. Voltage sensitive dyes (VSDs) have been introduced into this type of sensors only very recently, forming a new class of analytical tools. Here, K(+)-sensitive nanospheres incorporating a lipophilic VSD were successfully fabricated and characterized. The nanosensors were readily delivered into the social ...

Pial arterioles on the surface of the mouse brain were observed in vivo under a chamber with a glass window. When placed under the window, calcium ionophore, acetylcholine, and previously acidified sodium nitrite each dilated the arterioles. If the cyclooxygenase inhibitors indomethacin or acetylsalicylic acid were first placed in the chamber, subsequent dilation of the arterioles by calcium io...

The present study examined the effects of glutamate on the outgrowth of dendrites and axons in isolated hippocampal pyramidal-like neurons in cell culture. During the first day of culture the survival and outgrowth of these neurons was unaffected by high concentrations (up to 1 mu) of glutamate, quisqualic acid (QA), kainic acid (KA), and Kmethyl-D-aspartic acid. Beginning on day 2 of culture h...