Background and aim: Cutaneous leishmaniasis is an endemic disease in Iran. Although there are many different treatments for this disease, there is not any effective treatment yet. Since there has been a number of different reports on the effectiveness of Cassia fistula plant in the treatment of leishmaniasis, the efficacy of concentrated boiled extract and hydro alcoholic extract of Cassi...

Various extracts of flowers of Cassia fistula Linn (Leguminosae) such as petroleum ether (60-80°), chloroform, acetone, ethanol, aqueous, and crude aqueous extracts and two fractions of ethanol extract were tested for antihyperglycemic activity in glucose-overloaded hyperglycemic rats. The effective antihyperglycemic extracts and fraction were tested for their hypoglycemic activity at two dose ...

The aim of the study was to evaluate the synergistic antifungal action of crude DMSO (Di methyl sulphoxide) & Petroleum ether leaves extract of Cassia fistula in conjunction with fluconazole against candidial species isolated from Candidasis patients. Correlation was observed between the leaves & fluconazole, therefore it was also found that the antifungal action of Cassia fistula leaves extrac...

Diethylnitrosamine (DEN), found in many commonly consumed foods, is widely reported to induce cancer in animals and humans. The aim of the present study was to investigate the hepatoprotective and antioxidant activities of the leaf extract of the medicinal plant Cassia fistula Linn. against diethylnitrosamine induced liver injury in ethanol pretreated rats. Albino Wistar rats, pretreated with e...

The leaf extract of Cassia fistula with different solvens viz, methanol, benzene and acetone were studied for the larvicidal, ovicidal and repellent activity against Aedes aegypti. The extract exhibited dose dependent activity and produced significant mortality. The 24 h LC50 concentration of the extract against Aedes aegypti were observed at 10.69, 18.27 and 23.95 mg/l respectively. Mean perce...

The aqueous extract of the pods of Cassia fistula Linn (Leguminosae Caesalpinoideae), cultivated in Ile-Ife, Nigeria were investigated for pharmacological and toxicological properties. The in-vitro effect of Cassia fistula infusion on isolated guinea-pig ileum was examined. The acute and sub-chronic toxicity of the infusion of C. fistula and Cassia acutifolia Del. Pod(Senokot tablet) as the ref...

Objective: The plantCassia fistula L. (Caesalpiniaceae) is traditionally used to treat heart diseases, abdominal pain and fever. The present study was aimed to investigate the toxic effects acute and sub-acute administration of ethanol extract of C. fistula fruit (CFE) in male Wistar rats. Materials and Methods: In acute toxicity, the effects of a single oral dose (1000, 3000 and 5000 mg/kg) of...

Introduction and objective: Otitis externa, commonly called ear disease, is characterized by inflammation of the external ear canal. The aim of this study was to evaluate the antimicrobial potential of Cassia fistula flowers, leaves and bark extracts against Staphylococcus aureus, Proteus mirabilis, Escherchia coli, Pseudomonas aeruginosa, Acinetobacter sp., and Candida albicans, pathogens caus...

Petroleum ether extract of seeds of Cassia fistula was screened for the antifertility activity in proven fertile female albino rats at the doses 100, 200 and 500mg/kg b.wt./day. Oral administration of the extract to mated female rats on days 1-5 of pregnancy resulted in a decline in the fertility index, numbers of uterine implants and live fetuses in a dose dependent manner as was confirmed by ...