introduction: the field of stem cell biology and regenerative medicine is rapidly moving toward translation to clinical practice. stem cell therapy seems to be a new treatment option for some diseases. so, tracking the distribution of stem cells is crucial to their therapeutic use. based on this fact we labeled human mesenchymal stem cells (mscs) with 111in- oxine for the first time in our coun...

background: gallium-66 (t1/2= 9.49 h) is an interesting radionuclide that has potential for positron emission tomography (pet) imaging of biological processes in intermediate to slow target tissue uptake. oxine has been labeled with this radioisotope in the form of [66ga]gallium chloride for its possible diagnostic properties. materials and methods: 66ga was produced in the 30 mev cyclotron (cy...

background: the incorporation of thallium-201 into 8-hydroxyquinoline was targeted for cell labeling due to interesting physical properties and wide availability of this nuclide as a single photon emission computed tomography (spect) radionuclide. materials and methods: thallium-201 (t1/2=3.04 d) in tl+ form was converted to tl3+ cation in presence of o3/6m hcl and di-isopropyl ether, controlle...

  Introduction: The field of stem cell biology and regenerative medicine is rapidly moving toward translation to clinical practice. Stem cell therapy seems to be a new treatment option for some diseases. So, tracking the distribution of stem cells is crucial to their therapeutic use. Based on this fact we labeled human mesenchymal stem cells (MSCs) with 111...

introduction: due to the cell labeling potentials of various metal-maltol complexes, the idea of developing a possible cell labeling imaging agent using single photon emission computed chromatography (spect) with[111in]-maltolate complex has been investigated. methods: [111in] labeled 3-hydroxy-2-methyl-4h-pyran-4-onate ([111in]-maltolate) was prepared using freshly prepared [111in]incl3 and ...

Background: The incorporation of thallium-201 into 8-hydroxyquinoline was targeted for cell labeling due to interesting physical properties and wide availability of this nuclide as a single photon emission computed tomography (SPECT) radionuclide. Materials and Methods: Thallium-201 (T1/2=3.04 d) in Tl+ form was converted to Tl3+ cation in presence of O3/6M HCl and di-isopropyl ether, controlle...

Introduction: Due to the cell labeling potentials of various metal-maltol complexes, the idea of developing a possible cell labeling imaging agent using single photon emission computed chromatography (SPECT) with[111In]-maltolate complex has been investigated. Methods: [111In] labeled 3-hydroxy-2-methyl-4H-pyran-4-onate ([111In]-maltolate) was prepared using f...

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  Introduction: Radioimmunotherapy (RIT) is a very promising new therapy for the treatment of recurrent B-Cell non-Hodgkin's lymphoma (NHL). Iodine-131 is the most frequently used nuclide in clinical RIT, but its usefulness has been limited by dehalogenation of monoclonal antibodies labeled via conventional methods. To circumvent this problem, we have synthesized a tr...

introduction: radioimmunotherapy (rit) is a very promising new therapy for the treatment of recurrent b-cell non-hodgkin's lymphoma (nhl). iodine-131 is the most frequently used nuclide in clinical rit, but its usefulness has been limited by dehalogenation of monoclonal antibodies labeled via conventional methods. to circumvent this problem, we have synthesized a tri-peptide consisting of non-m...