Problem statement: The goal of the current investigation was to clarify the effects of Citrullus colocynthis pulp extract on the structure of the liver of diabetic rats at both light and scanning electron microscopic levels. Approach: Forty-eight adult male albino rats were equally allocated into four groups: Group1: control, Group 2: Citrullus colocynthis-treated, Group 3: diabetic rats and Gr...

OBJECTIVE To observe the effect of Citrullus colocynthis on beta cell regeneration and intra-islet vasculature. METHODS This experimental study was conducted at the University of Health Sciences, Lahore, Pakistan, from February 2013 to January 2014. It comprised male wistar rats weighing 100-150gand aged 6-8 weeks. The animals were divided into 6 groups. Group A1 served as control. Diabetes w...

BACKGROUND AND OBJECTIVES Inflammations and immune-related diseases including rheumatoid arthritis are widespread in the entire globe. The treatment of these illnesses is mainly based on the use of synthetic and biotechnological drugs, in recent years. Tunisian traditional medicine is a potential source of new remedies namely Citrullus colocynthis Schrad. (Cucurbitaceae): endemic in southern Tu...

Introduction: Diabetes is one of the most common diseases in this century. To cure this illness, herbal plants as well as medicine and diet therapy are used. This study is designed to determine the effect of citrullus colocynthis fruit pulp and seed on blood glucose in diabetic rabbits. Material and Methods: This experimental study was conducted on 36 white male New Zealand rabbits in animal la...

Citrullus colocynthis (Linn.) Schrad. is an important medicinal plant belonging to family Cucurbitaceae. Flavonoid "quercetin" was isolated from in vivo (leaf, stem, fruit and root) and in vitro callus of the species. The dried samples were separately soxhlet extracted in 80% methanol and then reextracted with petroleum ether, diethyl ether and ethyl acetate. The fraction was concentrated and s...

BACKGROUND Diabetes mellitus is one of the most common metabolic diseases in humans, affecting 100 million people around the world. OBJECTIVE Investigating the effects of Citrullus colocynthis pulp on oxidant and antioxidant factors of testes and epididymis in streptozotocin-induced diabetic male rats. MATERIALS AND METHODS Thirty two male rats were divided into four groups (n=8) 1) N (norm...

There is an increasing tendency for traditional medicine in the world. Many people prefer to take herbal products instead of chemical medicines. However, over consumption of herbal medicines has led to many unpredictable side effects.One of these traditional medicines is Citrullus colocynthis, which is used by diabetic patients as an hypoglycemic agent, but it has been reported to cause gastroi...

In the light of previous findings, the major aim of the present study was to investigate the potential beneficial effects of various Citrullus colocynthis L. seed extracts on such variables as glucose tolerance, body weight gain, pancreas, liver, kidney, testis, epididymal fat and diaphragm muscle weight, as well as serum cholesterol, triglyceride...