The aim of the present study was to further examine the efficacy of different doses and routes of D-cloprostenol and cloprostenol administration on the parturition response in sows. Ninety crossbred multiparous sows (Landrace x Yorkshire) with an average parity number of 4.3 ± 2.4 were allocated to induce farrowing by one of the following treatments: Gr. 1 (control, n=10) injection with normal ...

Methods: Two experiments were conducted. In experiment 1, sows received one of two treatments: either a single IM injection of 175 μg cloprostenol at day 113 of gestation (n=49) or an IM injection of 175 μg cloprostenol at day 113 of gestation followed by second IM injection of 175 μg cloprostenol 6 hours later (n=54). In experiment 2, sows received either a single (n=59) or a double (n=48) clo...

This study examined the use of PGF(2α) and estradiol benzoate (EB) either with or without GnRH to synchronize estrus in dairy cows for timed artificial insemination (TAI) under field conditions. First, Holstein dairy cows with a corpus luteum (CL) received 500 μg cloprostenol and were then randomly allocated to three groups: no further treatment (control, n=236); treatment with 1 mg EB 56 h aft...

AIM Bovine ovarian cysts are a common cause of economic loss in modern dairy herds. The objective of the present study was to evaluate the reproductive responses to three protocols using hCG, GnRH and cloprostenol when the definite diagnosis of the type of ovarian cyst is/is not possible in dairy cows. MATERIALS AND METHODS A total of 144 lactating dairy cows with ovarian cysts were divided i...

Objective. Evaluate the effectiveness of aglepristone with and without cloprostenol for treating canine pyometra. Materials and methods. Ten female French Bulldogs between 3-8 years of age diagnosed with pyometra were divided into two groups, one receiving a 10 mg/kg dose of aglepristone subcutaneously on days 1, 2, 8, 14 and 28, and the other an equal dose on days 1, 3, 8 and 15, as well as a ...

BACKGROUND The present study describes the clinical features and plasma profiles of bovine pregnancy-associated glycoprotein 1 (bPAG1), the main metabolite of prostaglandin F2alpha (PG metabolite) and progesterone (P4) in heifers in which early abortions were induced. METHODS Early abortions were induced in four heifers with cloprostenol and monitored by ultrasonography. Blood samples were co...

Using two PGF(2α) treatments 14 days apart as a way to enhance estrus detection rate following the 2nd treatment is a reproductive management tool that continues to be used on large dairy farms. In one study, in cows with a functional CL and a dominant follicle, treatment with cloprostenol vs. dinoprost resulted in greater peripheral estradiol concentrations. The objective of the present study ...

A dose determination study for the prostaglandin analogue cloprostenol was conducted in the Red Sokoto Does (RSD). 24 RSD were divided into four groups of 6 animals, the first group is the untreated control receiving 0μg of the cloprostenol. The second, third and fourth groups were given 50μg, 75 μg and 100 μg of the drug respectively. No oestrus response was observed in the control. All the an...

Experiments were conducted to determine the role of estrogens on endogenous PGF2 alpha secretion and luteolysis following injection of cloprostenol in heifers. In Exp. 1, eight luteal-phase heifers were used to evaluate tamoxifen (T) as an estrogen antagonist. Heifers received T (35 mg i.v.) or ethanol:saline vehicle (ES) every 4 h for 44 h. All received cloprostenol (500 micrograms i.m.) immed...

Ovarian cycle synchrony was assessed in spontaneously cycling female golden lion tamarins by monitoring longitudinal (16 mo) urinary steroid metabolite (estrone conjugates; pregnanediol-3 alpha-glucuronide, PdG) excretion in four pairs (n = 8) of females isolated from males. The overall mean ovarian cycle duration was 18.5 +/- 0.3 days (n = 136 cycles; mean range, 15.7-21.0 days), and there was...