Mechanical stress that arises due to deformation of the extracellular matrix (ECM) either stretches or compresses cells. The cellular response to stretching has been actively studied. For example, stretching induces phosphorylation of the myosin regulatory light chain (MRLC) via the RhoA/RhoA-associated protein kinase (ROCK) pathway, resulting in increased cellular tension. In contrast, the eff...

Magnetic shape memory properties of Ni-Mn-Ga single crystals were characterized by measurement of stress-induced martensite reorientation under constant magnetic fields. Also magnetic field-induced strain as a function of the applied magnetic field under different constant compressive stress levels has been investigated. All the experiments were performed at room temperature in which the sample...

The influence of in-plane residual stress on Hertzian nanoindentation for single-crystal copper thin film is investigated using molecular dynamics simulations (MD). It is found that: (i) the yield strength of incipient plasticity increases with compressive residual stress, but decreases with tensile residual stress; (ii) the hardness decreases with tensile residual stress, and increases with co...

Mechanically sensitive nociceptor afferents were studied in a preparation of isolated skin from rat leg. Each neuron was studied while the skin was subjected to tensile and compressive loading. The experiment was designed to create highly uniform states of stress in both tension and compression. Tensile loads were applied by pulling on the edges of the sample. Applied loads were used to determi...

A finite element analysis was conducted to determine the effect of moisture diffusion and hygroscopic swelling in rice. A parallel simple stochastic modeling was performed to predict the number of grains cracked as a result of moisture absorption and hygroscopic swelling. Rice grains were soaked in thermally (25C) controlled water and then tested for compressive stress. The destructive compress...

This paper compares the use of four mechanical methods for characterization of residual stress variation in low pressure chemical vapor deposited (LPCVD) polysilicon thin films deposited, doped, and annealed under different conditions. Stress was determined using buckling structures, vibrating microstructures, static rotating structures and the wafer curvature method. After deposition of 1.0 μm...

one important application of fiber reinforced polymer (frp) is to confine concrete as frp jackets in seismic retrofit process of reinforced concrete structures. confinement can improve concrete properties such as compressive strength and ultimate axial strain. for the safe and economic design of frp jackets, the stress-strain behavior of frp-confined concrete under monotonic and cyclic compress...

There exists some inconsistence regarding the true residual stress profiles by hard turning and grinding AISI 52100 steel (62 HRc). This study aims to clarify the pressing issues for five surface types: hard turned fresh, hard turned with a white layer, ground fresh, ground with a white layer, and as-heat-treated. The key findings are: (i) hard turned fresh surfaces produce surface compressive ...

Uncontrolled growth in a confined space generates mechanical compressive stress within tumors, but little is known about how such stress affects tumor cell behavior. Here we show that compressive stress stimulates migration of mammary carcinoma cells. The enhanced migration is accomplished by a subset of "leader cells" that extend filopodia at the leading edge of the cell sheet. Formation of th...

In order to quantitatively characterize the enhancement of hole mobility of strained silicon under different stress intensity conditions, changes of hole effective mass should be studied. In the paper, strained silicon under in-plane biaxially tensile strain based on (0 0 1) substrate and longitudinal uniaxially compressive strain along h1 1 0i are investigated thoroughly. By solving the Hamilt...