This paper is meant to question the idea that humans in cybernetic systems are autonomous in the traditional western liberal conception. Examination of the history of cybernetics reveals conflicts over the role of humans within human/machine systems over a larger period than is traditionally associated with the field of cybernetics. By comparing cybernetic systems from before the 20th century a...

Serendipity is defined as the discovery of a thing when one is not searching for it. In other words, serendipity means the discovery of information that provides valuable insights by unveiling previously unknown knowledge. This paper focuses on the problem of Linked Data serendipitous search. It first discusses how to capture a set of serendipity patterns in the context of Linked Data. Then, th...

The theoretical basis of a cybernetic metabolic network design and analysis framework, which has been subsequently successfully applied to predict system response to genetic alteration, is presented. This conceptual methodology consists of three main branches, namely, a model realization framework, a representation of genetic alteration, and lastly, a metabolic design component. These concepts ...

The cybernetic framework is a mathematical formalism developed by Ramkrishna and coworkers for modelling microbial systems. In this work, we analyze the dynamics of the cybernetic model for diauxic growth (Kompala et al., 1986, Biotechnol. Bioengng. 28 1044-1055). Recent data shows, however, that microbial growth on binary mixtures is frequently nondiauxic. The goal of this work is to: (1) Unde...