A double minimum six-dimensional potential energy surface (PES) is determined in symmetry coordinates for the most stable rhombic (D2h) B4 isomer in its 1Ag electronic ground state by fitting to energies calculated ab initio. The PES exhibits a barrier to the D4h square structure of 255 cm(-1). The vibrational levels (J=0) are calculated variationally using an approach which involves the Watson...

In situ RNA hybridization and immunocytochemistry were used to establish the cellular distribution of monoterpenoid indole alkaloid biosynthesis in Madagascar periwinkle (Catharanthus roseus). Tryptophan decarboxylase (TDC) and strictosidine synthase (STR1), which are involved in the biosynthesis of the central intermediate strictosidine, and desacetoxyvindoline 4-hydroxylase (D4H) and deacetyl...

Catharanthus roseus L. is an important medicinal plant producing several terpenoid indole alkaloids (TIAs) such as vincristine and vinblastine secondary metabolites with anticancer activity. The TIAs biosynthetic pathways are affected by biotic and abiotic stresses. In this study the effect of drought (7 days), salinity (150 mM NaCl), foliar spray of salicylic acid (10-5 M) and salicylic acid i...

The electrochemical behavior of rhodium at low-temperature carbamide-chloride and acetamide-chloride melts was investigated. It was found that, during rhodium anodic dissolution in carbamide and acetamide containing chloride melts, mixed complexes [Rh(NH3)4Cl2]+ of quasi-octahedral symmetry D4h are produced. The composition and structure of nascent complex ions have been studied. During electro...

For the emerging field of Design for Health (D4H) to realize its potential, it is necessary identify and address existing challenges faced by community. The few papers that have identified opportunities in confirm healthcare a challenging environment designers work in. In part this because design often misunderstood health professionals. This paper describes study sought understand future D4H G...

Sr2RuO4 and Fe-pnictide superconductors belong to the same point group symmetry D4h. Many experimental data confirm odd pairs in even Fe-pnictides, but opposite conclusions also exist. Recent NMR results of Pustogow et al., which revealed Cooper Sr2RuO4, require reconsideration treatment its SOP (superconducting order parameter). In present work making use Mackey–Bradley theorem on symmetrized ...

BACKGROUND The importance of the isatinic quinolyl hydrazones arises from incorporating the quinoline ring with the indole ring in the same compound. Quinoline ring has therapeutic and biological activities. On the other hand, isatin (1H-indole-2,3-dione) and its derivatives exhibit a wide range of biological activities. Also, the indole ring occurs in Jasmine flowers and Orange blossoms. Recen...

Cholesterol is an essential component of metazoan cellular membranes and it helps to maintain the structural integrity and fluidity of the plasma membrane. Here, we developed a cholesterol biosensor, termed D4H, based on the fourth domain of Clostridium perfringens theta-toxin, which recognizes cholesterol in the cytosolic leaflet of the plasma membrane and organelles. The D4H probe disassociat...

Cyclooctatetraene (COT), the first 4nπ-electron system to be studied, adopts an inherently nonplanar tub-shaped geometry of D2d symmetry with alternating single and double bonds, and hence behaves as a nonaromatic polyene rather than an antiaromatic compound. Recently, however, considerable 8π-antiaromatic paratropicity has been shown to be generated in planar COT rings even with the bond alter...