Liver metastasis has been found to affect outcome in prostate cancer and colorectal cancer, but its role in lung cancer is unclear. The current study aimed to evaluate the impact of de novo liver metastasis (DLM) on stage IV non-small cell lung cancer (NSCLC) outcomes and to examine whether tyrosine kinase inhibitors (TKI) reverse poor prognosis in patients with DLM and epidermal growth factor ...

BACKGROUND The aim of this study was to investigate the protective effects of L-glutamine (GLN) against liver and kidney injury caused by acute toxicity of deltamethrin (DLM). MATERIAL AND METHODS Thirty-two rats were indiscriminately separated into 4 groups with 8 rats each: control group (distilled water; 10 ml/kg, perorally [p.o.]), DLM group (35 mg/kg p.o. one dose.), GLN group (1.5 gr/kg...

BACKGROUND The purpose was to investigate prevalence of bilateral discoid lateral menisci (DLM) in Han Chinese patients who received surgery for symptomatic DLM, as well as a follow-up study of their asymptomatic contralateral knees using magnetic resonance imaging (MRI). METHODS A total of 110 patients [50 males and 60 females; average age: 21.95 ± 12.77 years (range: 6 to 67 years)] admitte...

The acute neurotoxicity of pyrethroid insecticides varies markedly with the dosage vehicle employed. The objective of the present study was to assess the influence of two common vehicles on the bioavailability and toxicokinetics (TK) of a representative pyrethroid insecticide, deltamethrin (DLM), to determine whether the vehicles influence toxic potency by modifying the chemical's TK. Adult, ma...

The Distributed L.ock Manager (DLM) is the cornerstone of running the Oracle Parallel Server on a MPP UNIX system. The DLM grants resource locks in NULL, READ, WRITE, and other levels. The DLM is typically implemented either with distributed message passing or in global shared memory, depending on the architecture. Reflective memory on the Encore Infinity 90 architecture permits a shared memory...

Two experiments were conducted to evaluate the efficacy of dietary DL-methionine hydroxy analog-free acid (MHA-FA, 88%) compared with DL-methionine (DLM, 99%) as Met sources in pigs. In Exp. 1, a total of 245 crossbred pigs (initial BW of 6.4 kg [SD = 0.5]) were allotted to 7 treatments in 7 replicates for an experimental period of 28 d. The basal diet (BD) was formulated to contain 17.5% CP an...

Two broiler experiments were conducted to assess the relative bioefficacy of liquid DL-Met hydroxy analog-free acid (MHA-FA) and DL-Met (DLM). Exponential regression analysis was used to determine biological efficacy based on body weight, feed conversion, and carcass responses to dietary Met source. In Trial 1, four graded inclusion levels of DLM and liquid MHA-FA (0.06, 0.12, 0.18, and 0.24%) ...

Poultry diets are typically supplemented with DL-2-hydroxy-4(methylthio) butanoic acid (HMTBA, or the hydroxy analog of methionine) or DL-methionine (DLM). Although HMTBA and DLM provide methionine activity, they are structurally distinct molecules with different physiological characteristics until they are converted to L-methionine. The relative rates of intestinal HMTBA vs. DLM absorption hav...

Recently, we have proposed the discrete Lagrange-multiplier method (DLM) to solve satissability problems. Instead of restarting from a new starting point when the search reaches a local minimum in the objective space, the Lagrange multipliers of violated constraints in DLM provide a force to lead the search out of the local minimum and move it in a direction provided by the multipliers. In this...

The standard methodology handling nonlinear PDE’s involves the two steps: numerical discretization to get a set of nonlinear algebraic equations, and then the application of the Newton iterative linearization technique or its variants to solve the nonlinear algebraic systems. Here we present an alternative strategy called direct linearization method (DLM). The DLM discretization algebraic equat...