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نتایج جستجو برای DMPC

تعداد نتایج: 594  
2013
Zuzanna Pietralik, Rafał Krzysztoń, Wojciech Kida, Weronika Andrzejewska, Maciej Kozak,

Amphiphilic dicationic surfactants, known as gemini surfactants, are currently studied for gene delivery purposes. The gemini surfactant molecule is composed of two hydrophilic "head" groups attached to hydrophobic chains and connected via molecular linker between them. The influence of different concentrations of 1,5-bis (1-imidazolilo-3-decyloxymethyl) pentane chloride (gemini surfactant) on ...

Journal: :Colloids and surfaces. B, Biointerfaces 2014
A P Serro, R Galante, A Kozica, P Paradiso, A M P S Gonçalves da Silva, K V Luzyanin, A C Fernandes, B Saramago,

Different types of lipid bilayers/monolayers have been used to simulate the cellular membranes in the investigation of the interactions between drugs and cells. However, to our knowledge, very few studies focused on the influence of the chosen membrane model upon the obtained results. The main objective of this work is to understand how do the nature and immobilization state of the biomembrane ...

Journal: :Biophysical journal 2007
D Constantin, G Brotons, A Jarre, C Li, T Salditt,

We have investigated the x-ray scattering signal of highly aligned multilayers of the zwitterionic lipid 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine containing pores formed by the antimicrobial peptide alamethicin as a function of the peptide/lipid ratio. We are able to obtain information on the structure factor of the pore fluid, which then yields the interaction potential between pores i...

Journal: :Biochimica et biophysica acta 2004
Amy C Rowat, James H Davis,

Involved in a number of diverse metabolic and functional contexts, farnesol is a central component of the mevalonate pathway, post-translationally attaches to proteins, and affects a number of other membrane-associated events. Despite farnesol's biological implications, a detailed analysis of how farnesol affects the physical properties and phase behaviour of lipid membranes is lacking. As (2)H...

2012
Pontus Giselsson, Anders Rantzer,

We consider distributed model predictive control (DMPC) where a sparse centralized optimization problem without a terminal cost or a terminal constraint set is solved in distributed fashion. Distribution of the optimization algorithm is enabled by dual decomposition.Gradient methods are usually used to solve the dual problem resulting from dual decomposition. However, gradient methods are known...

Journal: :Biophysical journal 2004
Andrey A Gurtovenko, Michael Patra, Mikko Karttunen, Ilpo Vattulainen,

Cationic lipid membranes are known to form compact complexes with DNA and to be effective as gene delivery agents both in vitro and in vivo. Here we employ molecular dynamics simulations for a detailed atomistic study of lipid bilayers consisting of a mixture of cationic dimyristoyltrimethylammonium propane (DMTAP) and zwitterionic dimyristoylphosphatidylcholine (DMPC). Our main objective is to...

Journal: :The journal of physical chemistry. B 2010
George Khelashvili, Georg Pabst, Daniel Harries,

We performed molecular dynamics (MD) simulations of hydrated bilayers containing mixtures of dimyristoylphosphatidylcholine (DMPC) and cholesterol at various ratios, to study the effect of cholesterol concentration on its orientation, and to characterize the link between cholesterol tilt and overall phospholipid membrane organization. The simulations show a substantial probability for cholester...

Journal: :Langmuir : the ACS journal of surfaces and colloids 2005
Thad A Harroun, Martin Koslowsky, Mu-Ping Nieh, Charles-François de Lannoy, V A Raghunathan, John Katsaras,

Mixtures of long- and short-chain phospholipids, specifically 14:0 and 6:0 phosphatidylcholines (DMPC and DHPC), have been used successfully in NMR studies as magnetically alignable substrates for membrane-associated proteins. However, recent publications have shown that the phase behavior of these mixtures is much more complex than originally thought. Using polarized light microscopy and small...

Journal: :Chemistry and physics of lipids 1998
H I Petrache, S Tristram-Nagle, J F Nagle,

X-ray diffraction data taken at high instrumental resolution were obtained for EPC and DMPC under various osmotic pressures, primarily at T = 30 degrees C. The headgroup thickness DHH was obtained from relative electron density profiles. By using volumetric results and by comparing to gel phase DPPC we obtain areas AEPCF = 69.4 +/- 1.1 A2 and ADMPCF = 59.7 +/- 0.2 A2. The analysis also gives es...

Journal: :Biophysical journal 2002
Stephanie Tristram-Nagle, Yufeng Liu, Justin Legleiter, John F Nagle,

The structure of fully hydrated gel phase dimyristoylphosphatidylcholine lipid bilayers was obtained at 10 degrees C. Oriented lipid multilayers were used to obtain high signal-to-noise intensity data. The chain tilt angle and an estimate of the methylene electron density were obtained from wide angle reflections. The chain tilt angle is measured to be 32.3 +/- 0.6 degrees near full hydration, ...