diamondoids are cage-like saturated hydrocarbons consisting of fused cyclohexane rings. thediamondoids family of compounds is one of the best candidates for molecular building blocks (mbbs)in nanotechnology to construct organic nanostructures compared to other mbbs known so far. thechallenge is to find a route for self-assembly of these cage hydrocarbons and their applications in thebottom-up s...

Diamondoids are cage-like saturated hydrocarbons consisting of fused cyclohexane rings. The Diamondoids family of compounds is one of the best candidates for molecular building blocks (MBBs) in nanotechnology to construct organic nanostructures compared to other MBBs known so far. The challenge is to find a route for self-assembly of these cage hydrocarbons and their applications in the bottom-...

Hyperbranched multiarm copolymers (HMCs) have shown great potential to be excellent precursors in self-assembly to form various supramolecular structures in all scales and dimensions in solution. However, theoretical studies on the self-assembly of HMCs, especially the self-assembly dynamics and mechanisms, have been greatly lagging behind the experimental progress. Herein, we investigate the e...

The glucocorticoid (GC) receptor (GR), when liganded to GC, activates transcription through direct binding to simple (+)GRE DNA binding sequences (DBS). GC-induced direct repression via GR binding to complex "negative" GREs (nGREs) has been reported. However, GR-mediated transrepression was generally ascribed to indirect "tethered" interaction with other DNA-bound factors. We report that GC-ind...

Abstract The unique specificity of DNA interactions and our ability to synthesize artificial functionalized sequences makes it the ideal material for controlling self-assembly chemical reactions components attached sequences. Inspired by field molecular electronics lack methods assemble components, we have explored organization conjugated using DNA-based self-assembly. In this chapter, provide ...

The Gal repressor regulates transport and metabolism of D-galactose in Escherichia coli and can mediate DNA loop formation by forming a bridge between adjacent or distant sites. GalR forms insoluble aggregates at lower salt concentrations in vitro, which can be solubilized at higher salt concentrations. Here, we investigate the assembly and disassembly of GalR aggregates. We find that a sharp t...

DNA is an ideal candidate to organize matter on the nanoscale, primarily due to the specificity and complexity of DNA based interactions. Recent advances in this direction include the self-assembly of colloidal crystals using DNA grafted particles. In this paper we theoretically study the self-assembly of DNA-caged particles. These nanoblocks combine DNA grafted particles with more complicated ...