نتایج جستجو برای: DNA index
تعداد نتایج: 895728 فیلتر نتایج به سال:
درمان سرطان به صورت قابل توجهی باعث افزایش طول عمر می شود. سیکلوفسفامید یک داروی ضدسرطان است که در شیمی درمانی استفاده می شود، جزء گروه های دارویی آنتی نئوبلاستیک آلکلیله کننده است که با آلکلیله کردن dna، rna آنزیم هایی را که سبب ساختن اسیدهای آمینه در پروتئین ها میشوند را مهار می کند. اثرات جانبی این دارو شامل بی اشتهایی، تهوع، کاهش عملکرد غدد جنسی، ایجاد آمنوره، آزواسپرمی، الیگو اسپرمی، اختلا...
Background: Various studies proposed virus infection is to be a possible cause of human breast cancer. However, the data argue the association between virus and cancer are inconsistent. This study was conducted to detect whether HPV-DNA is present in tissue samples of breast cancer in Isfahan province. Materials and Methods: Paraffin embedded formalin fixed specimens were prepared from 40 brea...
Abstract Background We aimed to develop and validate a predictive model for the overall survival (OS) of patients with nasopharyngeal carcinoma (NPC). Methods Overall, 519 were retrospectively reviewed in this study. In addition, random forest was used identify significant prognostic factors OS among NPC patients. Then, calibration plot concordance index (C-index) utilized evaluate accuracy nom...
BACKGROUND AND OBJECTIVES The continuous progress in treatment options for pancreatic adenocarcinoma has lead to a re-evaluation of prognostic markers. In this study the prognostic relevance of DNA Index and classical histopathological parameters with regard to disease-free (DFS) and overall survival (OS) was analyzed within the CONKO-001 patient population. METHODS One hundred forty three fr...
BACKGROUND We evaluated the prognostic importance of DNA ploidy in stage I and II endometrioid adenocarcinoma (EAC) of the endometrium with a focus on DNA index. PATIENTS AND METHODS High-resolution DNA ploidy analysis was carried out in tumor material from 937 consecutive patients with International Federation of Gynecology and Obstetrics (FIGO) stage I and II EAC of the endometrium. RESUL...
Tumor-released DNA in blood represents a promising biomarker for cancer detection. It has been postulated that tumor necrosis causes release of DNA of varying sizes, which contrasts apoptosis in normal tissue that releases smaller and more uniform DNA fragments. To test the hypothesis that increased DNA integrity, i.e., a longer DNA strand, is a tumor-associated marker in plasma, we determined ...
Out of 130 ovarian cancer patients the DNA index of cells from ovarian carcinoma was studied in 56 cases in which cytospin preparations showed the presence of atypical cells. In 24 patients the population had a diploid DNA index (1.0) and in the others the DNA index ranged from 1.2 to 2.0 (tetraploid). No hypodiploid or hypertetraploid populations were detected. Repeated samples from the same p...
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