Maternal hypothyroidism during pregnancy impairs brain function in human and rat offspring, but little is known regarding the influence of maternal hyperthyroidism on neurodevelopment. We have previously shown that the expression of neuronal and glial differentiation markers in fetal brain is compromised in hypothyroid rat dam pregnancies and have now therefore extended this investigation to hy...

Lactation is an important function that is dependent on changes in the maternal homeostasis and sustained by histological maternal adjustments. We evaluated how offspring manipulations during the lactational phase can modulate maternal morphologic aspects in the mammary gland, adipose tissue, and pancreatic islets of lactating dams. Two different models of litter-manipulation-during-lactation w...

Introduction In the foreword to the Malaysian Guidelines for Operation, Maintenance and Surveillance of Dams (Malaysian Inter-Departmental Committee on Dam Safety 1989), it is stated “The expanding inventory of dams has brought into focus the subject of dam safety”. At the time of the guideline publication, there had been a considerable increase in the inventory of dams with those constructed d...