Alkaloids, GS-MS, Datura stramonium The alkaloid spectrum in roots, leaves and seeds of Datura stramonium L. was investigated by GC-MS. Twenty-nine tropane alkaloids are detected. Twelve of them are new constituents for the species and the two tropane esters 3-(3'-acetoxytropoyloxy)tropane (21) and 3-(2'-hydroxytropoyloxy)tropane (26) are described for the first time.

Aqueous leaf extract of four different species of Datura viz. D.stramonium L., D. innoxia Mill.Gard, D. metal L. and D. ferox L. Amoen were tested for their antifungal activity against phytopathogenic molds in terms of mycelial growth of Alternaria solani and Fusarium oxysporum f.sp. udum causing early blight of tomato and wilt of pigeonpea respectively. The extract of Datura sp. at 5, 10, 15 a...

Three medicinal plants Abutilon mauritianum, Bacopa monnifera and Datura stramonium were assessed for phytochemical components and antimicrobial activity. The results revealed that all the three plant extracts contained saponins, tannins and alkaloids. Only Datura stramonium contained glycosides. The plants exert varying inhibitory effects on Pseudomonas aeruginosa, Klebsiella pneumonia and Esc...

Two case reports of Datura stramonium intoxications are presented. The first one was a self poisoning, with a moderate anticholinergic syndrome and a spontaneous improvement. The second one was a recreational use of Datura stramonium for its hallucinogenic properties. The anticholinergic syndrome was marked and the improvement required orotracheal intubation, mechanical ventilation, intraveinou...

plant tissue culture techniques were used to study the effect of nacl on tropane alkaloids accumulation and proline content of both datura metel and datura stramonium. callus cultures were established for both datura species. however, ms medium supplemented with 1mg/l of both ba and naa was the best for callus production in d. metel, while ms supplemented with 3 mg/l kin and 1 mg/l 2, 4-d was t...

Plant tissue culture techniques were used to study the effect of NaCl on tropane alkaloids accumulation and proline content of both Datura metel and Datura stramonium. Callus cultures were established for both Datura species. However, MS medium supplemented with 1mg/l of both BA and NAA was the best for callus production in D. metel, while MS supplemented wit...

Datura stramonium (DS) is a widespread annual plant, containing atropine, hyoscyamine, and scopolamine, which can produce poisoning with a severe anticholinergic syndrome. Teenagers ingest the roots, seeds or the entire plant to obtain its hallucinogenic and euphoric effects. We presented the case of a 22 year old male who was admitted to the Emergency Room in a coma after consuming Datura stra...

Plant tissue culture techniques were used to study the effect of NaCl on tropane alkaloids accumulation and proline content of both Datura metel and Datura stramonium. Callus cultures were established for both Datura species. However, MS medium supplemented with 1mg/l of both BA and NAA was the best for callus production in D. metel, while MS supplemented wit...

Three flavonoidal aglycones viz; F1 (Chrysin), F2 (Kampferol) and novel F3( 3,7dimethylether quercetin), were isolated from acetone wash of fresh leaves of Datura stramomium L. Isolated compounds were identified on the basis of their physico-chemical properties, Co-TLC, H-NMR, C-NMR and CIMS specrtum. Significant cytotoxic activity against three tumor cell lines (liver, cervix & breast), was re...