This paper presents a simulator tool that can simulate large databases of visually realistic longitudinal MRIs with known volume changes. The simulator is based on a previously proposed biophysical model of brain deformation due to atrophy in AD. In this work, we propose a novel way of reproducing realistic intensity variation in longitudinal brain MRIs, which is inspired by an approach used fo...

Background: Nickel-based superalloys are usually exposed to high static or cyclic loads in non-ambient environment, so a reliable prediction of their mechanical properties, especially plastic deformation, at elevated temperature is essential for improved damage-tolerance assessment of components. Methods: In this paper, plastic deformation in a single-crystal nickel-based superalloy CMSX4 at el...

This paper proposes an approach to effectively representing the statistics of high-dimensional deformations, when relatively few training samples are available, and conventional methods, like PCA, fail due to insufficient training. Based on previous work on scale-space decomposition of deformation fields, herein we represent the space of "valid deformations" as the intersection of three subspac...

This paper presents a novel approach for landmarkbased shape deformation, in which fitting error and shape difference are formulated into a support vector machine (SVM) regression problem. To well describe nonrigid shape deformation, this paper measures the shape difference using a thin-plate spline model. The proposed approach is capable of preserving the topology of the template shape in the ...

This paper presents an integrated approach for interactive direct volume deformation and simultaneous visualization. The fundamental requirement is that interactive performance without pre-processing must be achieved for large volume data, where at any time up to one million elements participate in a deformation that is applied interactively by picking and dragging in the 3D view. Current physi...

Contour tracking is a tough problem since the motion of the contour exhibits a complex dynamic process in which nonlinear deformation often occurs. This paper proposes a supervised approach to deformable contour tracking. The tracking system is built on a dynamic Bayesian network, which introduces one more hidden Markov process to switch among different contours. The contours are used to help t...

Since the 1970’s B-splines have evolved to become the de facto standard for use in curve and surface representation. This resulted in a relatively recent proliferation of nonrigid image registration techniques based on B-splines. These techniques fall under the general Free-Form Deformation (FFD) approach in which the object to be registered is embedded within a B-spline object. The deformation...

In order to take full advantage of the lightweight characteristics of composite materials, design often needs to sacrifice stiffness and exploit the more favourable strength. However, this approach leads to structures that deform significantly under load. This paper outlines a numerical methodology which demonstrates control of the inherent flexible characteristics of composite structures to ac...

OBJECTIVES A novel optical segment tracking (OST) approach reliant upon motion capturing was previously proposed to assess human tibia segment deformation. The purposes of the present study were to validate the OST approach and assess the contribution of muscular forces to the bone deformation in a well-defined ex vivo human model. METHODS A custom-made Lower Extremity Loading Device (LELD) w...