Dendrites achieve characteristic spacing patterns during development to ensure appropriate coverage of territories. Mechanisms of dendrite positioning via repulsive dendrite-dendrite interactions are beginning to be elucidated, but the control, and importance, of dendrite positioning relative to their substrate is poorly understood. We found that dendritic branches of Drosophila dendritic arbor...

introduction: appropriate thyroid hormone (th) levels are essential during the critical period of brain development, which is associated with the growth of axons and dendrites and synapse formation. in rats, oral motor circuits begin to reach to their adult pattern around 3 weeks after birth, the period in which alteration from sucking to biting and chewing occurs (weaning time). trigeminal mot...

Hippocampal pyramidal neurons have characteristic dendrite asymmetry, characterized by structurally and functionally distinct apical and basolateral dendrites. The ability of the neuron to generate and maintain dendrite asymmetry is vital, since synaptic inputs received are critically dependent on dendrite architecture. Little is known about the role of neuronal activity in guiding maintenance ...

Neurons develop highly stereotyped receptive fields by coordinated growth of their dendrites. Although cell surface cues play a major role in this process, few dendrite specific signals have been identified to date. We conducted an in vivo RNAi screen in Drosophila class IV dendritic arborization (C4da) neurons and identified the conserved Ret receptor, known to play a role in axon guidance, as...

The directional flow of information in neurons depends on compartmentalization: dendrites receive inputs whereas axons transmit them. Axons and dendrites likewise contain structurally and functionally distinct subcompartments. Axon/dendrite compartmentalization can be attributed to neuronal polarization, but the developmental origin of subcompartments in axons and dendrites is less well underst...

The directional flow of information in neurons depends on compartmentalization: dendrites receive inputs whereas axons transmit them. Axons and dendrites likewise contain structurally and functionally distinct subcompartments. Axon/dendrite compartmentalization can be attributed to neuronal polarization, but the developmental origin of subcompartments in axons and dendrites is less well underst...

objective(s):growing evidence indicates that extract of ginkgo biloba (egb) attenuates hippocampal-dependent memory deficit in aged individuals; however, very little is known about the effect of egb on the structure of hippocampus. therefore we examined the egb-induced morphological changes of the cornu ammonis (ca) region in aged rats. materials and methods: sixteen aged male wistar rats, 24 m...