نتایج جستجو برای: Dendritic Cell-Based Vaccine

تعداد نتایج: 4502938  

Journal: :acta medica iranica 0
saeid abediankenari department of immunology, immonogenetic research center, faculty of medicine, mazandaran university of medical sciences, sari, iran. ghasem janbabaei mollae department of hematology and oncology, mazandaran university of medical sciences, sari, iran. maryam ghasemi department of pathology, faculty of medicine, mazandaran university of medical sciences, sari, iran. yousef yousefzadeh department of immunology, immonogenetic research center, faculty of medicine, mazandaran university of medical sciences, sari, iran. masoud bahrami department of orthopedic, faculty of medicine, babol university of medical sciences, babol, iran. kamran alimoghaddam department of hematology and oncology, transplantation center, shariati hospital, tehran university of medical sciences, tehran, iran.

dendritic cells (dcs) are professional antigen presenting cells that have a potential role in the initiating of immune responses. the cell vaccination is a new strategy in treatment of infectious diseases and cancers. in this study, we have generated monocyte-derived dendritic cells of lymphoma patient's peripheral blood mononuclear cells then; these cells were used as vaccine in lymphoma patie...

Background: Melanoma is a common and malignant cutaneous tumor, which is responsible for a large proportion of skin cancer deaths. Dendritic cell (DC)-based vaccines have achieved positive results in the treatment of melanoma because of their ability to induce cytotoxic response to facilitate tumor elimination. Objective: To improve the efficacy of dendritic ce...

Introduction: Despite considerable efforts to control AIDS pandemic, it is still one of the significant infectious concerns worldwide. The advance in medical research has led to the development of highly active antiretroviral therapy with a considerable effect to suppress the disease. However, an effective vaccine capable of eradication the HIV pandemic is not available yet. Failure to develop ...

Ali Rezaie, Mohammad Abdollahi, Mohammad Hossein Yazdi, Mohammad Rostami-Nejad, Shekoufeh Nikfar,

Crohn's disease (CD) is an inflammatory disease of the gastrointestinal tract (GIT) tract and can affect several parts of the digestive system. There is a relationship between impaired mucosal barrier in the GIT of inflammatory bowel disease patients and the role of bacteria such as Mycobacterium avium paratuberculosis in CD. Apart from different therapeutic approaches for treating CD, developm...

Journal: :Journal of Hematological Malignancies 2011

Journal: :Turkish journal of medical sciences 2017
Si-Ming Wei Hang-Li Pan Li Wang Guo-Li Yin Kai Zhong Ya Zhou Shu-Jiao Yang Zhao-Liang Xin

BACKGROUND/AIM Dendritic cell-based vaccine therapy for renal cell carcinoma is effective but requires improvement. Here we explored whether combination therapy with dendritic cell-based vaccine and anti-CD69 antibody can enhance antitumor efficacy in renal cell carcinoma-bearing mice. MATERIALS AND METHODS Balb/c mice were challenged subcutaneously with murine renal cell carcinoma (Renca) ce...

2015
Si-Ming Wei Jin-Xuan Fei Feng Tao Hang-Li Pan Qing Shen Li Wang Yu-Jia Wu Li Zhou Sheng-Xin Zhu Wei-Bin Liao Hua Ji Zhao-Liang Xin

In the current study, we investigated whether anti-CD27 monoclonal antibody can enhance the antitumor efficacy of a dendritic cell-based vaccine in prostate cancer-bearing mice. The overall therapeutic effect of a dendritic cell-based vaccine for prostate cancer remains moderate. A prostate cancer model was established by subcutaneous injection of RM-1 tumor cells into male C57BL/6 mice on day ...

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