Background: Although advances in cancer therapy continue to develop, the overall survival rate is poor for some cancer cases. The search for a new adjuvant strategy is the focus of cancer treatment. There is some evidence suggesting a change in the mechanism of cell function by a change in the content of deuterium in the medium. So, the aim of this study was to investigate the ...

Measurements of the isotopic composition of stratospheric water by the ATMOS instrument are used to infer the convective history of stratospheric air. The average water vapor entering the stratosphere is found to be highly depleted of deuterium, with 6Dw of670 + 80 (67% deuterium loss). Model calculations predict, however, that under conditions of thermodynamic equilibrium, dehydration to strat...

BACKGROUND Oral administration of oxygenated water has been shown to improve blood oxygenation and could be an alternate way for oxygen (O2) supply. In this experiment, tissue oxygenation was compared in anesthetized pigs receiving a placebo or water enriched in O2 by injection or a new electrolytic process. METHODS Forty-two pigs randomized in three groups received either mineral water as pl...

RATIONALE Natural water samples artificially or experimentally enriched in deuterium ((2) H) at concentrations up to 10,000 ppm are required for various medical, environmental and hydrological tracer applications, but are difficult to measure using conventional stable isotope ratio mass spectrometry. METHODS Here we demonstrate that off-axis integrated cavity output (OA-ICOS) laser spectromet...

The mean deltaD value of petiole water of Pterocarpus indicus Willd (deltaD = -9.0 +/- 2.5 per thousand, n = 3) was not significantly different from the mean value of stem water (-8.3 +/- 2.8 per thousand, n = 3). deltaD values of main vein water ranged from -11.1 to + 12.0 per thousand (n = 14) and increased along the main vein from petiole to the tip of leaves. Mesophyll water was highly enri...

OBJECTIVE Isotope ratio mass spectrometry of hydrogen and oxygen is frequently used to determine total energy expenditure (TEE) using doubly labeled water. Conventionally, hydrogen isotope ratio is determined in hydrogen gas generated from water samples using zinc reduction. We compare this with a new automated platinum method to determine the ratios of hydrogen isotopes in deuterium-enriched w...

The use of stable isotopes in ecological studies requires that we know the magnitude of discrimination factors between consumer and element sources. The causes of variation in discrimination factors for carbon and nitrogen have been relatively well studied. In contrast, the discrimination factors for hydrogen have rarely been measured. We grew cabbage looper caterpillars (Trichoplusia ni) on ca...

Environmental factors can significantly affect disease prevalence, including neuropsychiatric disorders such as depression. The ratio of deuterium to protium in water shows substantial geographical variation, which could affect disease susceptibility. Thus the link between deuterium content of water and depression was investigated, both epidemiologically, and in a mouse model of chronic mild st...

abstract this study was carried out to investigate the hepatoprotective effect of deuterium depleted water with satureja rechingeri essential oil on liver damage. for this purpose, the adult male rats were divided into 16 groups. the negative control group used tap water in 14 days following dmso i.p injection at day 15th. the treatment group with acetaminophen received tap water in 14 days fol...

We describe how thermally produced anti-electron neutrinos (ν̄e) from the homologously collapsing core of a supermassive star (M ∼> 5 × 10 M⊙) can lead to significant deuterium enrichment in the ejected envelope of such a star. Deuterium-enriched material at high redshift might then serve as a clue to the existence of pregalactic supermassive stars. Conceivably, the ejected deuterium-enriched ma...